Actively Recruiting
Feasibility and Preliminary Efficacy of High-intensity Interval Training Combined with Muscle-strength Training in Older Women: Pilot Randomized Controlled Trial
Led by University of Nottingham · Updated on 2025-02-13
20
Participants Needed
1
Research Sites
17 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Women tend to live longer than men but often lose muscle mass faster due to inactivity, which can cause weakness and disability. Older women are generally less active, with many not meeting recommended levels of aerobic or strength exercise. High-intensity interval training (HIIT) offers a time-efficient and enjoyable way to exercise, and combining it with muscle strength training may yield better fitness improvements. This study evaluates whether combining HIIT with muscle strength training is practical and more effective than HIIT alone for older women. Participants will be randomly assigned to either a combined training group doing both muscle strength exercises and HIIT or a group doing HIIT only. Training sessions will last 30 minutes, three times a week for 12 weeks, with specific warm-ups, muscle exercises, and high-intensity intervals using a bike ergometer. Participants will attend exercise sessions and complete baseline and follow-up assessments measuring feasibility, functional capacity, muscle function, cardiorespiratory fitness, muscle mass, and quality of life over 12 weeks. The study includes monitoring adherence and evaluating health outcomes to understand the benefits and practicality of the exercise programs for older women.
CONDITIONS
Brief Title
High-intensity Interval Training Combined with Muscle-strength Training in Older Women
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female (biologically at birth)
- At least 60 years of age at the time of informed consent
- Non-smoker, including electronic cigarettes
- Not participating in routine high-intensity aerobic exercise (at least 75 minutes per week) or muscle strength training (at least twice per week)
- Able to perform a cardiopulmonary exercise test to exhaustion
- Willing to complete baseline and follow-up assessments
- Willing and able to attend prescribed exercise sessions at the University of Nottingham
- Able to give informed consent for participation
You will not qualify if you...
- Diagnosed with cardiovascular disease, kidney disease, diabetes, obstructive pulmonary disease, or uncontrolled hypertension
- History or current neurological or psychiatric illness, or motor or cognitive restrictions
- Contraindications to symptom-limited cardiopulmonary exercise testing, including resting hypertension with systolic blood pressure over 200 mmHg or diastolic blood pressure over 110 mmHg
- Uncorrected medical conditions such as significant anemia, important electrolyte imbalance, or hyperthyroidism
- Mental impairment limiting ability to cooperate
- Physical disability that prevents safe and adequate testing
- Participation in a research study within the last 3 months involving invasive procedures or receiving an inconvenience allowance
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 12 weeks
Participants attend 30-minute training sessions 3 times a week for 12 weeks, involving high-intensity interval training combined with muscle-strength training or aerobic training alone.
3 sessions per week (in-person)
Trial Site Locations
Total: 1 location
1
David Greenfield Humnn Physiology Unit (DGHPU), University of Nottingham
Nottingham, Nottingham, United Kingdom, NG72UH
Actively Recruiting
Research Team
T
Tasuku Terada, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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