Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID03524222

Home Hospital for Suddenly Ill Adults: A Clinical Trial

Led by Brigham and Women's Hospital · Updated on 2026-03-17

3000

Participants Needed

2

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Hospitals are the usual care setting for acute illnesses in the United States, but they can be costly and carry risks, especially for older adults. Many patients experience complications such as delirium, hospital-acquired infections, and lasting loss of function. Access to timely hospital care is often difficult due to overcrowding and long emergency department waits. This research aims to assess a home hospital model that provides acute care at home with similar quality and safety, while potentially reducing costs and improving patient experience compared to traditional hospital stays. The home hospital model offers many of the same medical services available in an acute care hospital, including care from doctors, nurses, and case managers, blood tests, vital signs monitoring, telemetry, x-rays, ultrasound, intravenous therapy, and oxygen or nebulizer treatments. Additional support such as food services, home health aides, physical and occupational therapy, and social work may be provided based on patient needs. Advanced technology like point-of-care blood diagnostics, continuous vital signs and activity tracking, and 24/7 video visits with clinicians are part of the care. If urgent in-person assistance is needed, emergency services will be called to transfer the patient back to the hospital. Participants will return home after initial evaluation and treatment in the emergency department and receive tailored home hospital services. They will be interviewed at discharge and 30 days after discharge about their hospitalization and health. Researchers will measure costs, length of stay, readmissions, medical tests, patient activity, sleep, quality of life, satisfaction, and safety indicators such as delirium and hospital transfers. The study is sponsored by Brigham and Women's Hospital and aims to evaluate total direct costs from admission to discharge, typically about four days.

CONDITIONS

Brief Title

Home Hospital for Suddenly Ill Adults

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Resides within either a 5-mile or 20 minute driving radius of emergency department
  • Has capacity to consent to study OR can assent to study and has proxy who can consent
  • 18 years or older
  • Can identify a potential caregiver who agrees to stay with patient for first 24 hours of admission and be available as needed afterwards; this may be waived for highly competent patients at clinician discretion
  • Primary or possible diagnosis requiring inpatient medical care, including cellulitis, heart failure, complicated urinary tract infection, pneumonia, COPD/asthma, infection, chronic kidney disease, malignant pain, diabetes complications, gout flare, hypertensive urgency, atrial fibrillation with rapid ventricular response, anticoagulation needs, or patient desires medical management requiring admission
Not Eligible

You will not qualify if you...

  • Undomiciled (homeless)
  • No working heat (October-April), no working air conditioning if temperature forecast is above 80°F (June-September), or no running water
  • On methadone requiring daily pickup of medication
  • In police custody
  • Resides in facility that provides on-site medical care (e.g., skilled nursing facility)
  • Positive domestic violence screen
  • Acute delirium as determined by Confusion Assessment Method
  • Cannot establish peripheral access in emergency department without ultrasound guidance
  • Secondary conditions such as end-stage renal disease, acute heart attack, stroke, or acute hemorrhage
  • Primary diagnosis requires multiple or routine intravenous narcotics for pain control
  • Cannot independently walk to bedside commode
  • Likely to require procedures like CT, MRI, endoscopy, blood transfusion, cardiac stress test, or surgery as deemed by on-call physician
  • High risk for clinical deterioration
  • Home hospital program is full (maximum 5 patients at a time)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person) during emergency department triage

Treatment

Duration - Approximately 4 days

Participants receive acute medical care at home through a specialized home hospital program, including diagnostics, intravenous therapy, and video visits with clinicians.

Continuous in-home care with on-demand clinician video visits and regular in-person visits as needed

Follow-up

Duration - 30 days post-discharge

Participants are interviewed regarding their hospitalization and health status at discharge and 30 days after discharge.

2 interviews (at discharge and 30 days after discharge)

Trial Site Locations

Total: 2 locations

1

Brigham and Women's Hospital

Boston, Massachusetts, United States, 02115

Actively Recruiting

2

Brigham and Women's Faulkner Hospital

Boston, Massachusetts, United States, 02130

Actively Recruiting

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Research Team

D

David M Levine, MD MPH MA

J

Jeffrey L Schnipper, MD MPH

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Frequently Asked Questions

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Published Research Related To This Trial

Hospital at home: feasibility and outcomes of a program to provide hospital-level care at home for acutely ill older patients.

Bruce Leff, Lynda Burton, Scott L Mader...

https://pubmed.ncbi.nlm.nih.gov/16330791

Costs for 'hospital at home' patients were 19 percent lower, with equal or better outcomes compared to similar inpatients.

Lesley Cryer, Scott B Shannon, Melanie Van Amsterdam...

https://pubmed.ncbi.nlm.nih.gov/22665835

Effects of a multicomponent intervention on functional outcomes and process of care in hospitalized older patients: a randomized controlled trial of Acute Care for Elders (ACE) in a community hospital.

S R Counsell, C M Holder, L L Liebenauer...

https://pubmed.ncbi.nlm.nih.gov/11129745