Actively Recruiting
How a Single Workout Affects Gut Bugs in Women With Different Fitness Levels and Body Types
Led by George Washington University · Updated on 2025-07-24
40
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to elucidate the differences in the gut microbiome functional activity and metabolome in adult premenopausal women with distinctive fitness levels and BMIs (with obesity, w/o obesity). The specific aims are as follows: * Aim 1: To examine the effects of acute aerobic exercise at 60-70% heart rate reserve (HRRmax) for 30 minutes bout on changes in the abundance of SCFA-producing bacteria and their functional downstream metabolic activity. * Aim 2: To examine the effects of acute aerobic exercise at 60-70% HRRmax 30-minute bout on changes in GM-released SCFA concentrations in stool and plasmatic metabolome.
CONDITIONS
Official Title
How a Single Workout Affects Gut Bugs in Women With Different Fitness Levels and Body Types
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Biological sex: female
- BMI between 19 and 24.99 kg/m2 or between 30 and 40 kg/m2
- Exercisers: Exercise at least 4 times per week for 60 minutes (total 240 minutes per week) in endurance, strength, or team sports
- Non-exercisers: Sedentary individuals not meeting physical activity guidelines (less than 150 minutes moderate or 75 minutes vigorous activity weekly)
You will not qualify if you...
- Biological sex: male
- BMI less than 19 kg/m2 or greater than 40 kg/m2
- Currently pregnant, less than 2 years postpartum, or lactating
- Taking any herbal, fiber, or prebiotic supplements
- Taking oral or vaginal antibiotics currently or within 1 month before the study
- Diagnosed with gastrointestinal, endocrine, digestive, cancer, or cardiovascular diseases
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Milken Institute School of Public Health, The George Washington University
Washington D.C., District of Columbia, United States, 20037
Actively Recruiting
Research Team
C
Carmen Ortega-Santos, PhD, RD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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