Testing Hyaluronic Acid Injection for Relieving Dry Mouth in Adults with Xerostomia A Double-Blind Study Comparing Treatment and Placebo Effects

What this Trial Is About

This research aims to find out if injecting hyaluronic acid under the mucous membrane can help relieve dry mouth symptoms in adults with xerostomia. The study will compare hyaluronic acid to a placebo to assess its effect on dry mouth sensation, side effects, duration of treatment benefits, and changes in saliva flow and pH. Participants will receive submucosal injections of either hyaluronic acid or a placebo solution throughout the mouth, including the floor of the mouth, cheek lining, and lips. Treatments will be given once monthly, and the study will last for six months with follow-up visits each month. During the study, participants will have monthly clinic visits for evaluations but will not need to perform any tasks at home. Researchers will monitor symptoms, saliva secretion, and safety throughout the six-month treatment period to understand the treatments effectiveness and any side effects.

Does Hyaluronic Acid Help Relieve Dry Mouth?