Actively Recruiting
Idiopathic Generalized Epilepsy: Cognitive, Emotional, Behavioral Functioning, and Quality of Life in Adolescents
Led by IRCCS National Neurological Institute "C. Mondino" Foundation · Updated on 2025-01-17
96
Participants Needed
1
Research Sites
108 weeks
Total Duration
On this page
Sponsors
I
IRCCS National Neurological Institute "C. Mondino" Foundation
Lead Sponsor
B
Buzzi Children's Hospital, Milan, Italy
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are studying adolescents aged 11 to 17 with idiopathic generalized epilepsy (IGE) to understand their neurocognitive, emotional-behavioral functioning, and quality of life. The study focuses on identifying key factors that influence the well-being of these patients, considering that IGE can be linked with mood disorders, ADHD, learning disabilities, and negative social outcomes despite generally normal neurocognitive development. The trial aims to explore these aspects using standardized assessments over one year. Participants will undergo emotional and neuropsychological assessments. Emotional-behavioral functioning and quality of life questionnaires are completed by patients and their caregivers during regular follow-up visits, while cognitive evaluations are conducted by clinicians using standardized tests. The study evaluates various epilepsy syndromes within IGE, which may include absence, myoclonic, and tonic-clonic seizures, with treatment often involving medication management. Throughout the one-year period, participants' cognition will be measured with standardized intelligence scales appropriate for their age. Quality of life, behavioral profiles, and executive functioning will be assessed using validated questionnaires. Clinical and medical history information will also be gathered to analyze influences on emotional and executive functioning. The study carefully monitors these outcomes to better understand the impact of IGE on adolescents' overall health and daily functioning.
CONDITIONS
Official Title
Idiopathic Generalized Epilepsy Cognitive and Emotional Profile
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 11 and 18 years
- Diagnosis of idiopathic generalized epilepsy
You will not qualify if you...
- Age under 11 years or over 18 years
- Structural or cryptogenic epilepsy
- Intellectual disability or borderline cognitive level
- Refusal to participate in the study
- Failure to obtain informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Clinical Trial Center
Pavia, Italy, 27100
Actively Recruiting
Research Team
V
Valentina De Giorgis, MD PhD
M
martina paola P. zanaboni, psy
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here