Actively Recruiting
Idiopathic Generalized Epilepsy: Cognitive, Emotional, Behavioral Functioning, and Quality of Life
Led by IRCCS National Neurological Institute "C. Mondino" Foundation · Updated on 2025-01-17
96
Participants Needed
1
Research Sites
21 weeks
Total Duration
On this page
Sponsors
I
IRCCS National Neurological Institute "C. Mondino" Foundation
Lead Sponsor
B
Buzzi Children's Hospital, Milan, Italy
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are studying adolescents aged 11 to 18 years with idiopathic generalized epilepsy (IGE) to understand their neurocognitive, emotional-behavioral functioning, and quality of life. The study aims to identify key factors that affect the overall well-being of these patients, considering that IGE can involve various seizure types and is often linked to mood disorders, ADHD, and learning difficulties. The research focuses on aspects beyond seizure control, such as psychological and social outcomes impacting health-related quality of life. Participants will undergo emotional and neuropsychological assessments during regular follow-up visits. Patients and their caregivers will complete standardized questionnaires about emotional-behavioral functioning and quality of life, while clinicians will conduct cognitive evaluations using standardized tools like the WISC IV and WAIS IV. This study is observational and does not involve drug treatments or interventions beyond assessments. Participants will be asked to complete questionnaires and undergo cognitive tests over a one-year period. Researchers will collect clinical and background information to analyze how various factors relate to emotional and executive functioning. The main outcomes measured include cognition, quality of life, behavioral profile, and executive functioning using specific standardized questionnaires and scales. The study also explores the connection between neurodevelopmental comorbidities and quality of life.
CONDITIONS
Brief Title
Idiopathic Generalized Epilepsy Cognitive and Emotional Profile
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 11 and 18 years
- Diagnosis of idiopathic generalized epilepsy
You will not qualify if you...
- Age under 11 years or over 18 years
- Structural or cryptogenic epilepsy
- Intellectual disability or borderline cognitive level
- Refusal to participate in the study
- Failure to obtain informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 1 year
Participants undergo emotional and neuropsychological assessments during regular follow-up visits to evaluate cognitive, emotional-behavioral functioning, and quality of life over time.
Regular follow-up visits as per routine care
Trial Site Locations
Total: 1 location
1
Clinical Trial Center
Pavia, Italy, 27100
Actively Recruiting
Research Team
V
Valentina De Giorgis, MD PhD
M
martina paola P. zanaboni, psy
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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