Actively Recruiting

Age: 11Years - 17Years
All Genders
ID06782074

Idiopathic Generalized Epilepsy: Cognitive, Emotional, Behavioral Functioning, and Quality of Life in Adolescents

Led by IRCCS National Neurological Institute "C. Mondino" Foundation · Updated on 2025-01-17

96

Participants Needed

1

Research Sites

108 weeks

Total Duration

On this page

Sponsors

I

IRCCS National Neurological Institute "C. Mondino" Foundation

Lead Sponsor

B

Buzzi Children's Hospital, Milan, Italy

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are studying adolescents aged 11 to 17 with idiopathic generalized epilepsy (IGE) to understand their neurocognitive, emotional-behavioral functioning, and quality of life. The study focuses on identifying key factors that influence the well-being of these patients, considering that IGE can be linked with mood disorders, ADHD, learning disabilities, and negative social outcomes despite generally normal neurocognitive development. The trial aims to explore these aspects using standardized assessments over one year. Participants will undergo emotional and neuropsychological assessments. Emotional-behavioral functioning and quality of life questionnaires are completed by patients and their caregivers during regular follow-up visits, while cognitive evaluations are conducted by clinicians using standardized tests. The study evaluates various epilepsy syndromes within IGE, which may include absence, myoclonic, and tonic-clonic seizures, with treatment often involving medication management. Throughout the one-year period, participants' cognition will be measured with standardized intelligence scales appropriate for their age. Quality of life, behavioral profiles, and executive functioning will be assessed using validated questionnaires. Clinical and medical history information will also be gathered to analyze influences on emotional and executive functioning. The study carefully monitors these outcomes to better understand the impact of IGE on adolescents' overall health and daily functioning.

CONDITIONS

Official Title

Idiopathic Generalized Epilepsy Cognitive and Emotional Profile

Who Can Participate

Age: 11Years - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 11 and 18 years
  • Diagnosis of idiopathic generalized epilepsy
Not Eligible

You will not qualify if you...

  • Age under 11 years or over 18 years
  • Structural or cryptogenic epilepsy
  • Intellectual disability or borderline cognitive level
  • Refusal to participate in the study
  • Failure to obtain informed consent

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Clinical Trial Center

Pavia, Italy, 27100

Actively Recruiting

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Research Team

V

Valentina De Giorgis, MD PhD

M

martina paola P. zanaboni, psy

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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