Actively Recruiting
Immunotherapy: Care and Prevention of Infectious and Tumoral Diseases (ImmunoHUB)
Led by Fondazione IRCCS Policlinico San Matteo di Pavia · Updated on 2025-04-06
40
Participants Needed
1
Research Sites
191 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The project comprises two research lines. In the line 1, human monoclonal antibodies toward SARS-CoV-2 will be generate and characterized by in vitro functional tests. In the line 2, in vitro tests will be performed to evaluate the efficency of immune response mediated by antibodies direct to specific tumor molecules.
CONDITIONS
Official Title
Immunotherapy: Care and Prevention of Infectious and Tumoral Diseases (ImmunoHUB)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age >18 at time of signing informed consent form
- Signed informed consent form
- For line 2: Primary liver tumor
You will not qualify if you...
- Active or history of neoplastic malignancy (line 1)
- Active autoimmune disease with ongoing immunosuppressive therapy
- Positive test for HIV, HCV, or HBV
- Diabetes
- Failure to sign informed consent form
- Concomitant diseases with life expectancy less than 12 months (line 2)
- Chronic autoimmune or inflammatory diseases (line 2)
- Treatment with certain cancer therapies including atezolizumab, bevacizumab, sorafenib, lenvatinib, regorafenib, cabozantinib, checkpoint inhibitors, tyrosine kinase inhibitors, or anti-VEGF therapies (line 2)
- Other extrahepatic cancers occurring or in last 3 years except for tumors resected with curative intent and no relapse for >3 years prior to consent and considered low risk of relapse (line 2)
- HIV infection (line 2)
AI-Screening
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Trial Site Locations
Total: 1 location
1
Fondazione IRCCS Policlinico San Matteo di Pavia
Pavia, Pavia, Italy, 27100
Actively Recruiting
Research Team
M
Mario Mondelli, MD
CONTACT
B
Barbara Oliviero, Biologist
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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