Study of Liver Hypertrophy Techniques in Patients with Liver Tumors in Italy Long-term Observation of Outcomes After Liver Surgery

What this Trial Is About

This study is an observational research project conducted across multiple centers in Italy to understand and describe changes over time in the use of techniques for inducing liver growth hepatic hypertrophy. It focuses on patients with liver tumors or cancer who require liver surgery but have a future liver remnant volume considered too small by their medical teams. The goal is to compare and understand different methods used over recent years to help guide treatment decisions. Participants are observed according to the usual care practices at their treatment centers. The study includes two groups a prospective group followed from recruitment and observed for up to five years after liver surgery to record health events, and a retrospective group made up of patients treated with these hypertrophy techniques in the past ten years. This historical data will be used to compare with the new patient group to better understand trends and outcomes. Throughout the study, information about patients health status, including survival and disease progression, will be collected regularly. Researchers will track various outcomes such as liver function, growth in liver volume, dropout rates from treatment, short-term mortality within 90 days, long-term survival, and disease-free survival. This comprehensive follow-up helps to evaluate the effectiveness and safety of the different hypertrophy techniques used in clinical practice in Italy.

Italian Group of Regenerative and Occlusive Worldwide-used Techniques of Hepatic Hypertrophy