Actively Recruiting
The Impact of a 48-hour Fast with or Without Exercise on Immune Cell Metabolism and Glycemic Control in Healthy Active Adults
Led by University of British Columbia · Updated on 2025-03-07
15
Participants Needed
1
Research Sites
29 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Many individuals engage in fasting for its purported health benefits but the effects of fasting on immune cell and whole body metabolism are not well understood in humans. Moreover, how exercising during a prolonged fast impacts immunometabolic outcomes is unclear. This study will determine how a 2 day fast - performed with or without daily exercise - impacts immune cell bioenergetics, immune cell function, and whole-body glycemic control in healthy active individuals.
CONDITIONS
Official Title
The Impact of a 48-hour Fast with or Without Exercise on Immune Cell Metabolism and Glycemic Control in Healthy Active Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 19 and 35 years.
- Physically active, engaging in at least 150 minutes of moderate to vigorous physical activity each week.
You will not qualify if you...
- History of cardiometabolic or inflammatory diseases such as COPD, rheumatoid arthritis, or cardiovascular disease.
- Currently following a ketogenic diet, low-calorie diet, periodic fasting regimen, or using ketogenic supplements.
- Cigarette or vaping smoking.
- Physical limitations that impair ability to exercise.
- Body mass index over 30 kg/m2.
- Cancer diagnosis within the past 5 years.
- Taking anti-inflammatory medications such as ibuprofen, aspirin, or naproxen.
- Unable to read or communicate in English.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of British Columbia Okanagan Campus
Kelowna, British Columbia, Canada, V1V1V7
Actively Recruiting
Research Team
J
Jonathan Little Principal Investigator, Professor Little, Ph.D
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
OTHER
Number of Arms
2
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