Actively Recruiting
Led by Medical University of South Carolina · Updated on 2025-11-12
39
Participants Needed
1
Research Sites
21 weeks
Total Duration
Researchers are evaluating whether multiple sessions of photobiostimulation using an Nd-YAG laser can improve healing after tooth extraction and alveolar ridge preservation. This study aims to measure the effects of laser treatment on wound healing by examining saliva markers, tracking changes in gingival wound size, and assessing post-operative pain and patient satisfaction. The research focuses on enhancing recovery and comfort following dental surgery. Participants will be divided into two groups: one receiving standard tooth extraction and alveolar ridge preservation with sham laser (control group), and the other receiving the same procedure combined with Nd-YAG laser photobiostimulation on days 1, 3, and 7 after surgery. The laser will be applied using a LightWalker® device with specific settings, and both participants and operators will wear protective glasses during treatments. During the study, participants will have their saliva tested for inflammation markers from the day of surgery through day 7. Wound size changes will be monitored up to day 42, and pain levels will be recorded from day 3 to day 14 after surgery. Researchers will also survey patients about pain relief and satisfaction. The total participation period may last up to 42 days, including follow-up assessments to observe healing progress and safety.
CONDITIONS
Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 7 days
Participants undergo tooth extraction and alveolar ridge preservation. Low-level laser therapy or a sham laser is applied on the day of extraction, and then on day 3 and day 7 to support healing at the treatment site.
3 visits (in-person) on day 1, day 3, and day 7
Duration - Up to 42 days
Participants are monitored for wound healing and post-operative pain after the treatment period.
Visits to assess wound healing and pain typically occur from day 3 through day 42
Total: 1 location
1
MUSC College of Dental Medicine, Graduate Periodontics Clinic
Charleston, South Carolina, United States, 29425
Actively Recruiting
P
Pinar Emecen-Huja
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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