Actively Recruiting
Impact of the New Generation Anti-diabetic Drugs on Diabetic Retinopathy
Led by Sara A Belal · Updated on 2026-01-20
70
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to test the impact of new-generation anti-diabetic drugs, such as SGLT2 inhibitors and DPP-4 inhibitors, on the development of diabetic retinopathy (DR). The study hypothesizes that these drugs have protective effects in diabetic retinopathy by delaying its incidence compared to older agents (including metformin) only. Early intervention is critical, as treatment options for advanced stages of DR are limited in terms of their ability to restore impaired vision and their high associated costs. By focusing on delaying the occurrence of diabetic retinopathy, the investigators aim to reduce the burden of DR and improve the quality of life for diabetic patients.
CONDITIONS
Official Title
Impact of the New Generation Anti-diabetic Drugs on Diabetic Retinopathy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with Type 2 Diabetes for more than 5 years
- Using diabetes medications (metformin, sulfonylureas, SGLT2 inhibitors, DPP-4 inhibitors) for 2 to 3 years
You will not qualify if you...
- Gestational Diabetes
- Type 1 Diabetes
- Severe non-proliferative diabetic retinopathy at baseline
- Proliferative diabetic retinopathy at baseline
- Pregnant and breastfeeding women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Alexandria University Main Hospitals - Diabetes clinics/ Ophthalmology clinics
Alexandria, Egypt
Actively Recruiting
Research Team
S
Sara A Belal
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here