Actively Recruiting
Feasibility and Acceptability of an Individualized Online Home-Based Exercise Program on Psychoneurological Symptoms in Gynecologic Cancer Survivors: A Pilot Study
Led by Emory University ยท Updated on 2025-09-11
40
Participants Needed
4
Research Sites
52 weeks
Total Duration
On this page
Sponsors
E
Emory University
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating an individualized online home-based exercise program designed to improve symptoms and quality of life in women who have survived gynecologic cancers such as uterine, ovarian, and cervical cancer. This study aims to understand how this exercise program affects the gut microbiome and symptoms including pain, fatigue, sleep problems, depression, and cognitive difficulties, which can significantly impact survivors' well-being and survival. The trial is a pilot study focusing on the feasibility and acceptability of this approach. Participants first meet with a certified exercise trainer to complete a fitness assessment using a treadmill or a 6-minute walk test. They then take part in a 12-week exercise program conducted via Zoom, which involves progressive, moderate-intensity walking based on how hard they feel they are working. Sessions last about 30 minutes and occur twice a week, with social support provided during the exercise. Participants also wear an activity tracker to monitor their physical activity. Throughout the study, participants are assessed for their adherence to the program and its acceptability. Researchers collect data on changes in gut microbiome and psychoneurological symptoms from the start to the end of the 12 weeks. Additional measures include quality of life, eating habits, and stress levels. The study monitors participants' progress and experiences closely to understand the program's impact on their health and symptoms.
CONDITIONS
Brief Title
An Individualized Online Home-Based Exercise Program for Improving Symptoms in Gynecologic Cancer Survivors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women aged 63 18 years old
- Previously diagnosed with gynecologic cancer such as uterine, ovarian, or cervical cancer
- Completed cancer treatment including chemotherapy or chemoradiation
- Able to read and speak English
- Do not meet recommended exercise levels as defined by The American College of Sports Medicine
You will not qualify if you...
- History of metastatic or other primary cancer
- Serious mental health conditions such as bipolar disorder, schizophrenia, or major depression
- Certain chronic diseases including muscular-skeletal diseases limiting mobility, autoimmune diseases, uncontrolled diabetes, hypertension, or renal disease with creatinine > 2.5 mg/dL
- Unable to read or speak English
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) for eligibility assessment
Duration - 1 day
Participants meet with a certified exercise trainer and complete a functional capacity assessment using a treadmill or 6-minute walk test.
1 visit (in-person)
Duration - 12 weeks
Participants complete an individualized online home-based exercise intervention via Zoom consisting of progressive, moderate-intensity walking and receive social support.
Twice-weekly online sessions (30 minutes each)
Trial Site Locations
Total: 4 locations
1
Grady Health System
Atlanta, Georgia, United States, 30303
Actively Recruiting
2
Emory University Hospital Midtown
Atlanta, Georgia, United States, 30308
Actively Recruiting
3
Emory University Hospital/Winship Cancer Institute
Atlanta, Georgia, United States, 30322
Actively Recruiting
4
Emory Decatur Hospital
Decatur, Georgia, United States, 30033
Actively Recruiting
Research Team
Z
Zahra Barandouzi, Ph.D.,MSN,RN
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
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