Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
ID06709534

Feasibility and Acceptability of an Individualized Online Home-Based Exercise Program on Psychoneurological Symptoms in Gynecologic Cancer Survivors: A Pilot Study

Led by Emory University ยท Updated on 2025-09-11

40

Participants Needed

4

Research Sites

52 weeks

Total Duration

On this page

Sponsors

E

Emory University

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating an individualized online home-based exercise program designed to improve symptoms and quality of life in women who have survived gynecologic cancers such as uterine, ovarian, and cervical cancer. This study aims to understand how this exercise program affects the gut microbiome and symptoms including pain, fatigue, sleep problems, depression, and cognitive difficulties, which can significantly impact survivors' well-being and survival. The trial is a pilot study focusing on the feasibility and acceptability of this approach. Participants first meet with a certified exercise trainer to complete a fitness assessment using a treadmill or a 6-minute walk test. They then take part in a 12-week exercise program conducted via Zoom, which involves progressive, moderate-intensity walking based on how hard they feel they are working. Sessions last about 30 minutes and occur twice a week, with social support provided during the exercise. Participants also wear an activity tracker to monitor their physical activity. Throughout the study, participants are assessed for their adherence to the program and its acceptability. Researchers collect data on changes in gut microbiome and psychoneurological symptoms from the start to the end of the 12 weeks. Additional measures include quality of life, eating habits, and stress levels. The study monitors participants' progress and experiences closely to understand the program's impact on their health and symptoms.

CONDITIONS

Brief Title

An Individualized Online Home-Based Exercise Program for Improving Symptoms in Gynecologic Cancer Survivors

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Women aged 63 18 years old
  • Previously diagnosed with gynecologic cancer such as uterine, ovarian, or cervical cancer
  • Completed cancer treatment including chemotherapy or chemoradiation
  • Able to read and speak English
  • Do not meet recommended exercise levels as defined by The American College of Sports Medicine
Not Eligible

You will not qualify if you...

  • History of metastatic or other primary cancer
  • Serious mental health conditions such as bipolar disorder, schizophrenia, or major depression
  • Certain chronic diseases including muscular-skeletal diseases limiting mobility, autoimmune diseases, uncontrolled diabetes, hypertension, or renal disease with creatinine > 2.5 mg/dL
  • Unable to read or speak English

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person) for eligibility assessment

Functional Assessment

Duration - 1 day

Participants meet with a certified exercise trainer and complete a functional capacity assessment using a treadmill or 6-minute walk test.

1 visit (in-person)

Treatment

Duration - 12 weeks

Participants complete an individualized online home-based exercise intervention via Zoom consisting of progressive, moderate-intensity walking and receive social support.

Twice-weekly online sessions (30 minutes each)

Trial Site Locations

Total: 4 locations

1

Grady Health System

Atlanta, Georgia, United States, 30303

Actively Recruiting

2

Emory University Hospital Midtown

Atlanta, Georgia, United States, 30308

Actively Recruiting

3

Emory University Hospital/Winship Cancer Institute

Atlanta, Georgia, United States, 30322

Actively Recruiting

4

Emory Decatur Hospital

Decatur, Georgia, United States, 30033

Actively Recruiting

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Research Team

Z

Zahra Barandouzi, Ph.D.,MSN,RN

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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