Insights Into Tick-Borne Diseases: a Prospective Study From an Endemic Area of Northern Italy

What this Trial Is About

Researchers are conducting an experimental, non-drug and non-device study focused on tick-borne diseases in a region of Northern Italy where these infections are common. The purpose is to monitor and analyze individuals who have been bitten by ticks to better understand the infections transmitted by ticks and their impact. This monocentric study involves detailed visits and blood sampling that go beyond usual medical care practices. Participants will have an initial visit within 7 to 10 days after a tick bite, which includes signing consent forms, collecting data, and drawing blood samples. A follow-up visit occurs 12 weeks later to assess clinical and serological changes. If symptoms suggestive of tick-borne diseases appear, participants will have an additional unscheduled visit with further blood collection. If infections like TBEV, Rickettsia, Borrelia, Ehrlichia, Anaplasma, or Babesia are diagnosed, treatment will follow standard medical guidelines. Throughout the study, participants will undergo blood tests to detect antibodies and molecular testing on ticks and blood samples to identify specific tick-borne pathogens. Researchers will track how many people develop infections and antibodies during the 12-week follow-up. The study includes monitoring symptoms and collecting leftover samples stored at very low temperatures. Participation involves multiple visits and tests over about three months with careful monitoring of health and laboratory results.

Insights Into Tick-Borne Diseases: a Study From an Endemic Area of Northern Italy