Two Cases of Borrelia miyamotoi Meningitis, Sweden, 2018.
Anna J Henningsson, Hilmir Asgeirsson, Berit Hammas...
https://pubmed.ncbi.nlm.nih.gov/31538916Actively Recruiting
Age: 1Year +
All Genders
Healthy Volunteers
ID06781008
Emerging Tick-borne Diseases in Children and Adults in Sweden (SWEtick): a Prospective Multicenter Study for Improved Patient Management
Led by Region Jönköping County · Updated on 2026-03-05
600
Participants Needed
12
Research Sites
260 weeks
Total Duration
On this page
Sponsors
R
Region Jönköping County
Lead Sponsor
R
Region Östergötland
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are conducting a prospective multicenter study in Sweden called SWEtick to better understand emerging tick-borne diseases (eTBD). The study aims to explore the different ways these diseases present clinically, assess their impact on human health, develop and validate diagnostic laboratory methods, and create recommendations to improve patient care within the Swedish healthcare system. The study includes several patient groups: those with confirmed tick-borne diseases, those suspected of having tick-borne diseases but diagnosed otherwise, patients undergoing spinal anesthesia during knee or hip replacement surgery due to arthrosis, patients with autoinflammatory joint diseases, and healthy blood donors. This observational study gathers data from these diverse groups to support its goals. Participants will be followed and evaluated using tools such as the EuroQoL-5 Dimension Questionnaire (EQ-5D) and the Visual Analogue Scale for Health (VAS) at six months to assess health outcomes. The study involves collecting clinical information, symptoms, and laboratory results to support diagnosis and management. Participation may last several months, with ongoing data collection and assessments to better understand tick-borne diseases and their effects.
CONDITIONS
Brief Title
SWEtick - a Prospective Multicenter Study of Tick-borne Diseases in Sweden
Who Can Participate
Age: 1Year +
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Clinical suspicion of tick-borne disease based on a physician's assessment including medical history, symptoms, clinical findings, and sometimes lab results
- Participants aged 1 year or older
- Both children and adults of all genders
You will not qualify if you...
- Adults and adolescents older than 15 years who are unable to understand study information and make decisions
AI-Screening
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Complete this quick 3-step screening to check your eligibility
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Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Monitoring
Duration - Up to 6 months
Participants are observed over time to collect information related to tick-borne diseases and their health status.
Periodic visits during 6 months
Trial Site Locations
Total: 12 locations
1
Department of Paediatrics
Falun, Region Dalarna, Sweden
Actively Recruiting
2
Department of Paediatrics, Eksjö Hospital
Eksjö, Region Jönköping County, Sweden, 575 81
Actively Recruiting
3
Department of Infectious Diseases, County Hospital Ryhov
Jönköping, Region Jönköping County, Sweden, 55185
Actively Recruiting
4
Department of Paediatrics
Jönköping, Region Jönköping County, Sweden, 55185
Actively Recruiting
5
Department of Infectious Diseases, Kalmar County Hospital
Kalmar, Region Kalmar County, Sweden, 392 56
Actively Recruiting
6
Department of Infectious Diseases
Uppsala, Region Uppsala, Sweden
Not Yet Recruiting
7
Department of Paediatrics
Uppsala, Region Uppsala, Sweden
Not Yet Recruiting
8
Department of Paediatrics
Örebro, Region Örebro County, Sweden
Not Yet Recruiting
9
Department of Infectious Diseases, Linköping University Hospital
Linköping, Region Östergötland, Sweden, 581 85
Actively Recruiting
10
Department of Infectious Diseases, Vrinnevi Hospital
Norrköping, Region Östergötland, Sweden, 603 79
Actively Recruiting
11
Department of Paediatrics, Vrinnevi Hospital
Norrköping, Region Östergötland, Sweden, 603 79
Actively Recruiting
12
Department of Paediatrics
Skövde, Västra Götalandsregionen, Sweden
Not Yet Recruiting
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Research Team
A
Anna J Henningsson, Senior Associate Professor
J
Johanna Sjöwall, Associate Professor (docent)
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
5
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Published Research Related To This Trial
First documented case of human babesiosis in Sweden.
I Uhnoo, O Cars, D Christensson...
https://pubmed.ncbi.nlm.nih.gov/1411322Spiroplasma ixodetis Infections in Immunocompetent and Immunosuppressed Patients after Tick Exposure, Sweden.
Johannes Eimer, Louise Fernström, Louise Rohlén...
https://pubmed.ncbi.nlm.nih.gov/35876734[Varying clinical picture and course of human granulocytic ehrlichiosis. Twelve Scandinavian cases of the new tick-borne zoonosis are presented].
A Bjöersdorff, J Berglund, B E Kristiansen...
https://pubmed.ncbi.nlm.nih.gov/10544585Rickettsia helvetica in patient with meningitis, Sweden, 2006.
Kenneth Nilsson, Karin Elfving, Carl Pahlson
https://pubmed.ncbi.nlm.nih.gov/20202426Association of Rickettsia helvetica with chronic perimyocarditis in sudden cardiac death.
K Nilsson, O Lindquist, C Påhlson
https://pubmed.ncbi.nlm.nih.gov/10513711Ten years of detecting Neoehrlichia mikurensis infections in Sweden: demographic, clinical and inflammatory parameters.
Christine Wennerås, Linda Wass, Beatrice Bergström...
https://pubmed.ncbi.nlm.nih.gov/39136831Tick-borne diseases under the radar in the North Sea Region.
Hanne Quarsten, Anna Henningsson, Karen A Krogfelt...
https://pubmed.ncbi.nlm.nih.gov/37116420Laboratory Methods for Detection of Infectious Agents and Serological Response in Humans With Tick-Borne Infections: A Systematic Review of Evaluations Based on Clinical Patient Samples.
Anna J Henningsson, Audun Aase, Herjan Bavelaar...
https://pubmed.ncbi.nlm.nih.gov/34616701