Integrated Cancer Repository for Cancer Research

What this Trial Is About

Researchers are creating and maintaining the Integrated Cancer Repository for Cancer Research iCaRe2, a multi-institutional resource gathering detailed, ongoing data and biospecimens from adult cancer patients, people at high risk, and healthy controls. This platform covers a wide geographic area, including many small and rural hospitals, to support comprehensive studies on cancer risks, development, progression, and to aid in designing new prevention, screening, early detection, and personalized treatment strategies. The iCaRe2 collects multi-dimensional cancer-related data and biospecimens such as tumor specimens, DNA, serum, urine, and plasma from various cancer registries covering numerous cancer types, including pancreatic, breast, thyroid, lung, gastrointestinal, genitourinary, central nervous system, blood cancers, skin cancers, and more. It uses a flexible confederation model allowing multiple centers to participate based on their expertise and resources. The platform is web-based, HIPAA compliant, and supports secure data collection, validation, standard vocabularies, and reporting. Participants provide informed consent and may include those diagnosed with cancer, at risk for cancer, or healthy controls. Data collection includes longitudinal monitoring and banking of biological materials for future study. Researchers measure the development and implementation of this web-based cancer registry and the procurement of biological materials over many years. Participants involvement includes data sharing and biospecimen donation, supporting studies in cancer biology, genetics, epidemiology, early detection, and patient care, with ongoing follow-up up to many years.

Integrated Cancer Repository for Cancer Research