Actively Recruiting
Interest of Follicular Helper Lymphocytes / Regulatory Follicular Helper Lymphocytes Ratio in IgA Nephropathy
Led by Centre Hospitalier Universitaire de Besancon · Updated on 2024-11-21
75
Participants Needed
1
Research Sites
153 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to investigate the relevance of the Tfh/Tfr (Follicular helper T cells/ Follicular regulatory T cells) ratio in patients with IgA nephropathy: * To identify a differential expression of the Tfh/Tfr ratio in patients considered stable or progressive * To predict, at diagnosis, the clinical evolution of the disease (progressive or stable form) in the first year.
CONDITIONS
Official Title
Interest of Follicular Helper Lymphocytes / Regulatory Follicular Helper Lymphocytes Ratio in IgA Nephropathy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with IgA nephropathy confirmed by kidney biopsy with at least 8 permeable glomeruli
- Diagnosis made since 2009 with a minimum of 5 years follow-up for arm 1 patients
- Diagnosis made during the study for arm 2 patients
- Control group includes patients with lupus, ANCA-associated vasculitis, or polycystic kidney disease (arm 3)
You will not qualify if you...
- Legal incapacity or limited legal capacity
- No social security coverage
- Pregnancy or no effective contraceptive method
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Centre Hospitalier Universitaire de Besançon
Besançon, France, 25000
Actively Recruiting
Research Team
C
Charline Vauchy, PhD.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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