Actively Recruiting

Age: 4Years - 99Years
All Genders
Healthy Volunteers
ID05418218

International Headache and Vertigo Registration Study

Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2025-05-23

200000

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

S

Second Affiliated Hospital, School of Medicine, Zhejiang University

Lead Sponsor

Z

Zhejiang University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are studying patients aged 4 to 99 years who experience various types of headaches, vertigo conditions, and chronic pain, including migraine, tension-type headache, vestibular migraine, and fibromyalgia. This international registration study aims to investigate biomarkers, imaging features, heart-lung shunts, genetic characteristics, treatments, and outcomes related to these headache-related disorders with planned long-term follow-up. Participants are grouped by headache and vertigo types, including migraine (all types), other primary headache disorders, vertigo disorders excluding vestibular migraine, secondary headache disorders, and a group of normal individuals without headache or vertigo. The study collects detailed clinical data and assessments, focusing on real-world treatment and disease characteristics. Participants will undergo evaluations including symptom diaries, biomarker tests, various MRI imaging methods, echocardiography, and questionnaires measuring headache impact, disability, quality of life, mental health, and physical function. The study tracks outcomes such as migraine and headache days, attack frequency, pain intensity, and physiological measures over medium and long-term periods, with continuous monitoring planned for up to 60 years.

CONDITIONS

Brief Title

International Headache Registry Study

Who Can Participate

Age: 4Years - 99Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Provide written informed consent and privacy authorization before any study procedures
  • Male or female participants aged 4 to 99 years at the first visit
  • Diagnosed with primary or secondary headaches per ICHD-3 criteria, including migraine, tension-type headache, vestibular migraine, or other headache disorders in the ICHD-3 appendix
Not Eligible

You will not qualify if you...

  • Unable to complete headache diaries or related scales
  • Declined or unable to participate in long-term follow-up

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Within 6 months after initial diagnosis

Participants undergo assessments including biomarkers, imaging, heart shunt evaluations, and genetic studies related to headache and vertigo conditions.

1 to 2 visits depending on diagnostic procedures

Long-term Monitoring

Duration - Up to 60 years

Participants are followed over long-term periods to monitor outcomes such as migraine days, headache intensity, and quality of life measures.

Periodic follow-up visits as scheduled during the study

Trial Site Locations

Total: 1 location

1

Kaiming Liu

Hangzhou, Zhejiang, China, 370001

Actively Recruiting

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Research Team

K

Kaiming Liu, Doctor

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

5

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