Actively Recruiting
Investigating Genetic Status in Patients Presenting to Clinic
Led by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Updated on 2025-03-04
1000
Participants Needed
1
Research Sites
1032 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The causes of neurodegenerative dementias such as Frontotemporal Dementia, Lewy Body Disease and Alzheimer's disease are still largely unknown. While the contribution of some genetic mutations and polymorphisms is associated with autosomal dominant patterns of inheritance of these dementias, in many cases, the specific causative mutation in these families is not yet identified. Further, in many patients, polygenic risk is thought to give rise to pathophysiologic changes, but which specific genes affect risk are largely yet unknown. By examining genotypes in patients that present to our Cognitive Neurology and Alzheimer's Research Clinic with suspected or confirmed neurodegenerative dementia, or have a history of a familial dementia, we aim to help identify and characterize genetic mutations or polymorphisms that give rise to neurodegenerative diseases.
CONDITIONS
Official Title
Investigating Genetic Status in Patients Presenting to Clinic
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Persons presenting to the cognitive clinic with a neurodegenerative disorder such as Alzheimer's disease, Frontotemporal Dementia, Lewy Body Dementia, ALSP, or related conditions
- Biological family members of someone diagnosed with a neurodegenerative disorder presenting to clinic
- Age 18 years or older
- Willing and able to consent to a blood draw
You will not qualify if you...
- Persons who decline, are unwilling, or unable to have a blood draw
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Parkwood Institute
London, Ontario, Canada, N6C 0A7
Actively Recruiting
Research Team
S
Sarah Jesso
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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