Actively Recruiting
Investigating Genetic Status in Patients Presenting to Clinic
Led by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Updated on 2025-03-04
1000
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating genetic factors that may contribute to neurodegenerative dementias such as Frontotemporal Dementia, Lewy Body Disease, and Alzheimer's disease. The study aims to identify and understand genetic mutations or polymorphisms that could cause these conditions, especially in patients with suspected or confirmed neurodegenerative dementia or those with a family history of such disorders. Many genetic causes remain unknown, making this research important for uncovering potential genetic risks. Participants will undergo a one-time blood draw to collect biosamples for genetic testing. This involves a brief visit lasting approximately 20 minutes during which the genetic status or polymorphism results will be obtained. The study is observational and does not involve any treatment or intervention beyond the collection of blood samples. During the visit, demographic information, medical history, and clinical or pathological diagnoses will be recorded, typically within one month of the clinic visit. The study primarily measures genetic results from the blood sample, with additional data collected to support the research. Participants will have a single study visit, and no long-term follow-up is described. The total participation time is limited to about 20 minutes for the main procedures.
CONDITIONS
Brief Title
Investigating Genetic Status in Patients Presenting to Clinic
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Persons presenting to the cognitive clinic with a neurodegenerative disorder such as Alzheimer's disease, Frontotemporal Dementia, Lewy Body Dementia, ALSP, or related conditions
- Biological family members of someone diagnosed with a neurodegenerative disorder presenting to clinic
- Age 18 years or older
- Willing and able to consent to a blood draw
You will not qualify if you...
- Persons who decline, are unwilling, or unable to have a blood draw
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 1 day
Participants provide a blood sample for genetic testing and provide demographic and medical information.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
Parkwood Institute
London, Ontario, Canada, N6C 0A7
Actively Recruiting
Research Team
S
Sarah Jesso
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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