Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT07038733

Investigation of Lymph Node Biology in Kidney Cancer

Led by Yale University · Updated on 2026-02-03

10

Participants Needed

1

Research Sites

95 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this pilot study is to investigate the phenotype, anti-tumor effector functions, and TCR repertoire of T cells isolated from patient tumor draining lymph nodes (TDLNs) to understand T cell priming and trafficking patterns in Renal Cell Carcinoma (RCC). Data and biospecimen collected will be used for current and future research projects involving the study of kidney cancer biology and related medical conditions. We will use this valuable resource to ask clinically relevant translational questions that pertain to biomarker discovery/validation, identification of novel therapeutic targets, and to better understand the genetic and biological basis of the various kidney cancers.

CONDITIONS

Official Title

Investigation of Lymph Node Biology in Kidney Cancer

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients with known or suspected kidney cancer referred to Yale Genitourinary Oncology providers
  • Receiving clinical evaluation, medical treatment, surgery, or procedures at Yale New Haven Hospital or Smilow Cancer Hospital
  • Eligibility determined by study investigators who will provide protocol details
  • Consent obtained by investigators or authorized study personnel
  • Patients of non-study physicians may participate with approval from their treating physician
Not Eligible

You will not qualify if you...

  • Participants under 18 years of age
  • Pregnant or actively breastfeeding individuals
  • Known allergy or hypersensitivity to iodine

AI-Screening

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Trial Site Locations

Total: 1 location

1

Yale University

New Haven, Connecticut, United States, 06510

Actively Recruiting

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Research Team

S

Stephanie Ladd

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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