Actively Recruiting
Investigation of Preoperative Factors Influencing the Outcome of Motor Deficits in Patients Undergoing Lumbar Microdiskectomy
Led by Aristotle University Of Thessaloniki · Updated on 2026-02-17
40
Participants Needed
3
Research Sites
26 weeks
Total Duration
On this page
Sponsors
A
Aristotle University Of Thessaloniki
Lead Sponsor
H
Hippocration General Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Motor deficits like lower limb weakness caused by lumbar disc herniation often require surgical treatment through microdiscectomy. This observational study aims to identify preoperative factors that may affect how well patients recover muscle strength after microdiscectomy for lumbar disc herniation. Researchers will examine factors such as severity and duration of paresis, age, body mass index, diabetes, and characteristics of the herniated disc. The study will include patients with motor deficits due to lumbar disc herniation who are scheduled for a single-level lumbar microdiscectomy. It is a prospective multicenter study involving three neurosurgical departments. Researchers will analyze primary factors like muscle strength and duration of paresis before surgery, along with secondary factors including obesity, diabetes, disc location, and morphology. Participants will be evaluated for muscle strength using the Medical Research Council Scale before and after surgery to categorize their recovery as full, partial, or none. Additional assessments include pain levels, functionality, and quality of life. The study plans to enroll 40 patients and will follow them through the perioperative period to understand how these preoperative factors influence surgical outcomes.
CONDITIONS
Brief Title
Investigation of Preoperative Factors Influencing the Outcome of Motor Deficits in Patients Undergoing Lumbar Microdiskectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients suffering from lower limb paresis (motor deficit) caused by lumbar disk herniation undergoing a single-level microdiskectomy
- Age (years) > 17
You will not qualify if you...
- Age (years) < 18
- Medical history of lumbar spine surgery
- Absence of limb paresis
- Motor deficit caused by other than disk herniation aetiologies
- Reoperation within 6 months after microdiskectomy
- Microdiskectomy at more than one level
- Cauda equina syndrome
- Peripheral neuropathy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to hospital discharge
Participants undergo lumbar microdiscectomy and receive immediate care following the surgery.
1 surgical procedure and immediate post-operative care
Duration - Several weeks to months post-surgery
Participants are followed after surgery to monitor muscle strength recovery and assess pain, functionality, and quality of life.
Multiple follow-up visits for muscle strength and recovery assessments
Trial Site Locations
Total: 3 locations
1
General Hospital of Kavala
Kavala, Greece, 65500
Actively Recruiting
2
Hippokration General Hospital
Thessaloniki, Greece, 54642
Actively Recruiting
3
European Interbalkan Medical Center
Thessaloniki, Greece, 57001
Actively Recruiting
Research Team
P
Panagiotis Sarlis
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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