Actively Recruiting
Iodine Uptake After a Low Iodine Diet
Led by University Medical Center Groningen · Updated on 2026-02-06
25
Participants Needed
1
Research Sites
183 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare the difference in thyroid uptake of a low dose radioactive iodine (10 MBq 123-I or 37 MBq 123-I) in athyreotic patients with differentiated thyroid carcinoma before and after a low iodine diet (LID) of 7 days. The main question it aims to answer is: • What is the difference in iodine uptake before and after a LID of 7 days? Uptake of a low dose of 123-iodine will be measured in participants before and after a low iodine diet of 7 days. Researchers will compare the uptake (%) before and after the LID.
CONDITIONS
Official Title
Iodine Uptake After a Low Iodine Diet
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 years or older diagnosed with differentiated thyroid carcinoma (DTC)
- Patients scheduled to follow a low iodine diet before 131I ablation therapy according to Dutch DTC guidelines
- Patients fit to follow the study protocol
- Patients able to read and understand Dutch
You will not qualify if you...
- Age below 18 years
- Current use of amiodarone medication
- Received iodinated contrast within 3 months before starting the low iodine diet
- Pregnancy
- Preparation for ablation therapy using rhTSH
- Renal impairment with EGFR less than 30 ml/min/1.73 m2
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UMCG
Groningen, Provincie Groningen, Netherlands, 9713GZ
Actively Recruiting
Research Team
W
Wouter Zandee, Dr.
CONTACT
M
Mirthe Links, BSc.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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