Actively Recruiting

Age: 18Years +
All Genders
NCT05471752

Isolation, Characterization and Evaluation of the Potential of TissuE-resideNt cElls From Waste Musculoskeletal and Associated Connective Tissues

Led by I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio · Updated on 2022-07-25

742

Participants Needed

1

Research Sites

260 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The general purpose of this study is characterization of tissue-resident cells derived from different musculoskeletal and/or associated connective tissues (such as cartilage, synovial membrane, synovial fluid, bone, adipose tissue and tendons), in order to identify new strategies for the treatment of degenerative and inflammatory musculoskeletal disorders. Cells isolated from different tissue sources will be compared with each other by phenotypic and functional characterization, following culture and treatment with inflammatory elements, drugs and orthobiologics. Moreover, with the aim to assess predictive markers of therapeutic success, a correlation study of the content and properties of the cells isolated from different types of tissue with the clinical profile of the enrolled patients will be conducted.

CONDITIONS

Official Title

Isolation, Characterization and Evaluation of the Potential of TissuE-resideNt cElls From Waste Musculoskeletal and Associated Connective Tissues

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female
  • 18 years old or older
  • Undergoing elective surgery at IRCCS Istituto Ortopedico Galeazzi, including joint surgery such as hip or knee replacement, ACL reconstruction, or rotator cuff repair
Not Eligible

You will not qualify if you...

  • Under 18 years old
  • Unable to sign the Informed Consent
  • Positive test for HIV, HCV, HBV, or syphilis (TPHA)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IRCCS Istituto Ortopedico Galeazzi

Milan, Italy, 20161

Actively Recruiting

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Research Team

D

Direzione Scientifica

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Isolation, Characterization and Evaluation of the Potential of TissuE-resideNt cElls From Waste Musculoskeletal and Associated Connective Tissues | DecenTrialz