Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
ID04705766

The KIDCOV Study: Assessment of SARS-CoV-2 Without Hospitalization as a Risk Factor for Acute Kidney Injury

Led by University of California, San Francisco · Updated on 2025-07-28

2000

Participants Needed

3

Research Sites

N/A

Total Duration

On this page

Sponsors

U

University of California, San Francisco

Lead Sponsor

R

Rush University Medical Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research aims to understand the impact of mild or sub-clinical COVID-19 infection in adults on kidney injury over a 12-month period. It addresses a gap in knowledge about kidney damage in outpatients with COVID-19 by studying both COVID-19 positive and negative individuals across diverse racial and ethnic backgrounds from California, Michigan, and Illinois. The goal is to gather data that can help guide prevention and treatment strategies for COVID-19 related kidney injury. Participants will be grouped into COVID-19 positive and negative cohorts. They will receive mailed urine collection kits at 2, 6, and 12 months after their COVID-19 PCR test to provide samples for biomarker analysis. No in-person visits are required, and the main focus is on measuring the urine-based KIT Score and other markers like NGAL and KIM-1 to track kidney injury over time. Throughout the study, participants will complete questionnaires and send urine samples by mail. Researchers will analyze these samples for biomarkers indicating kidney injury and compare results between the groups. The primary measurement is the continuous KIT Score after one year. This remote participation allows monitoring without leaving home, supporting safety and convenience over the study duration.

CONDITIONS

Brief Title

KIDney Injury in Times of COVID-19 (KIDCOV)

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Result of PCR-based COVID-19 test conducted in the past 4 weeks posted in EMR of participating academic medical centers
  • Age 18 years or older at enrollment
  • Provide race/ethnicity, sex, age, and phone and/or home/email address
Not Eligible

You will not qualify if you...

  • Failure to provide written informed consent
  • Hospitalization within 4 weeks after SARS-CoV-2 test
  • History of kidney transplant
  • History of dialysis treatment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - Up to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 contact via email or text to invite participation and complete online consent

Surveillance

Duration - 12 months

Participants are observed over 12 months to assess kidney injury through urine biomarker analysis.

Urine collection at 2, 6, and 12 months via mailed kits

Trial Site Locations

Total: 3 locations

1

UCSF

San Francisco, California, United States, 94143

Actively Recruiting

2

Rush University

Chicago, Illinois, United States, 60612

Actively Recruiting

3

University of Michigan

Ann Arbor, Michigan, United States, 48109

Actively Recruiting

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Research Team

M

Minnie Sarwal, M.D., Ph.D.

T

Tara Sigdel, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Published Research Related To This Trial