Actively Recruiting
Laparoscopic Versus Robotic Lateral Transabdominal Adrenalectomy: a Single-center Randomized Prospective Trial
Led by The Cleveland Clinic · Updated on 2026-02-02
54
Participants Needed
1
Research Sites
17 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to compare two minimally invasive surgical methods for adrenalectomy: laparoscopic and robotic lateral transabdominal adrenalectomy. Both procedures are standard care options for removing adrenal tumors. The study seeks to assess differences in patient outcomes and surgeon efficiency to help improve care and optimize resource use in adrenal surgery. Participants will undergo either laparoscopic or robotic adrenalectomy, with 27 patients assigned to each group through randomization. Laparoscopic surgery uses straight instruments with two-dimensional video guidance, while robotic surgery involves wristed instruments and a three-dimensional video system. This single-center trial is conducted at a high-volume adrenal surgery program with expertise in both techniques. During the study, researchers will measure the time from skin incision to closure as the primary outcome. Secondary outcomes include conversion rates between approaches, postoperative pain scores, hospital stay length, and cost. Participants will be closely monitored throughout their hospital stay and recovery, with assessments occurring at specified time points. The study will help clarify the advantages and challenges of each surgical method over the course of treatment and recovery.
CONDITIONS
Brief Title
Laparoscopic Versus Robotic Lateral Transabdominal Adrenalectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and women between ages 18 and 75
- Diagnosis of an adrenal tumor or pathology planned for minimally invasive adrenalectomy at the Cleveland Clinic endocrine surgery department
You will not qualify if you...
- Requirement for open adrenalectomy due to imaging suggesting aggressive cancer
- Extensive prior surgical history preventing minimally invasive approach
- Planned partial adrenalectomy instead of complete adrenalectomy
- Planned posterior adrenalectomy due to extensive abdominal adhesions or bilateral adrenalectomy
- Mental incapacity or language barrier
- Any other condition or unwillingness that risks safety or study compliance per clinician judgment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo either laparoscopic or robotic transabdominal adrenalectomy as a minimally invasive surgical treatment for adrenal tumors.
1 surgical procedure and hospital stay for up to 3 days
Duration - 3 days
Participants are monitored post-surgery for recovery, pain assessment, and hospital stay duration.
Approximately 3 post-operative visits
Trial Site Locations
Total: 1 location
1
The Cleveland Clinic Foundation
Cleveland, Ohio, United States, 44195
Actively Recruiting
Research Team
K
Kimberly Jenkins
A
Andrea Parianos
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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