Actively Recruiting

All Genders
NCT04288674

Leptospirosis Registry - LeptoScope

Led by University of Cologne · Updated on 2025-12-17

200

Participants Needed

1

Research Sites

560 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Leptospirosis is a worldwide zoonotic diseases caused by pathogenic Leptospira spp. Human are accidental hosts, who acquired infections after exposition to animal urine, contaminated water or soil, infected tissue. Incidence of invasive leptospirosis disease causing acute kidney injury, acute respiratory distress syndrome (ARDS), myocarditis, hepatic dysfunction, hemorrhage and multi-organ failure, is globally increasing and there have been frequent outbreak situation throughout the world. Due to increasing outbreak situations and globally chances in species distributions, a worldwide surveillance in epidemiology and species distribution is urgently needed. The objective of the Leptospirosis Registry - LeptoScope is to overcome the lack knowledge on epidemiology, clinical course, prognostic factors and molecular characteristics for invasive leptospirosis disease.

CONDITIONS

Official Title

Leptospirosis Registry - LeptoScope

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Cultural, serological, molecular, or histological evidence of invasive leptospirosis disease
  • Clinical signs of disseminated leptospirosis disease without such laboratory evidence
  • Case controls matched by demographics, underlying diseases, and hospitalization duration from the same hospitals
Not Eligible

You will not qualify if you...

  • Colonization or other non-invasive infection
  • Evidence of leptospirosis without dissemination by culture, serology, molecular, or histology

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital of Cologne

Cologne, North Rhine-Westphalia, Germany, 50937

Actively Recruiting

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Research Team

F

Felix Köhler, MD

CONTACT

F

Felix Köhler, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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