Lifestyle Intervention to Reduce Dementia Risk in Older Adults with Cognitive Decline A Randomized Trial Comparing Personalized Coaching and General Health Advice

What This Trial Is About

Researchers are studying how lifestyle changes can help older adults aged 50 and above who have subjective cognitive decline SCD or mild cognitive impairment MCI, conditions that increase the risk of developing dementia. This trial tests the effects of a one-year lifestyle intervention compared to general health advice in reducing dementia risk. The study aims to evaluate both the effectiveness and cost-effectiveness of this lifestyle program and explore how it can be sustainably implemented in memory clinics. Participants are randomly assigned to one of two groups. Group A receives a tailored lifestyle intervention that includes three individual sessions with a lifestyle coach, a voucher program to encourage brain-healthy activities, and access to an online self-management tool for dementia risk reduction. Group B receives general health advice through regular healthcare and informational materials. Both interventions last for 12 months. During the study, participants will be assessed at the start and after one year. Researchers will measure changes in dementia risk using the Lifestyle for Brain Health LIBRA score, cognitive functions like memory and attention, and physical health indicators such as blood pressure, cholesterol, and body mass index. Questionnaires will gather information on lifestyle habits, quality of life, social support, and knowledge about dementia risk. Data on healthcare use and productivity costs will also be collected to evaluate cost-effectiveness. The total participation time is one year.

Lifestyle Intervention in the Memory Clinics of General and Academic Hospitals Trial