Actively Recruiting
The Link Between Physical Activity and Brain Health in Healthy Adults
Led by Technical University of Madrid · Updated on 2025-06-17
60
Participants Needed
1
Research Sites
92 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to investigate the cross-sectional relationship between physical activity and brain health from a multiscale approach (neuropsychology, neuroimaging, peripheral biomarkers and genetics) in former athletes and sedentary individuals. The main question it aims to answer is: Do former athletes have better brain structure than sedentary people? Evaluating the differences in neurodegenerative processes between competitive training and sedentary and inactivity.
CONDITIONS
Official Title
The Link Between Physical Activity and Brain Health in Healthy Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ex-athletes who currently exercise regularly at least 3 days per week with moderate to vigorous intensity
- Sedentary individuals performing less than 150 minutes of moderate exercise per week or with IPAQ score under 600 MET min/week
- Participants must have maintained their physical activity or sedentary lifestyle for at least 6 months prior to evaluation
- No history of neurological or psychiatric disorders or serious medical conditions
You will not qualify if you...
- Medical conditions with high risk of cognitive symptoms
- Severe head injury with loss of consciousness within the last 5 years
- Alcoholism (more than 3 alcoholic drinks per day)
- Chronic use of anxiolytics, neuroleptics, narcotics, anticonvulsants, or sedative hypnotics
- Hearing or visual impairments that prevent testing
- History of neurological diseases affecting cognition (e.g., cerebrovascular disease)
- Brain structural abnormalities affecting cognition or survival (e.g., malignant brain tumor)
- Severe systemic diseases such as cancer under treatment
- Use of anabolic substances
- Difficulty understanding spoken or written Spanish
- Presence of pacemakers or metallic implants interfering with MRI
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Faculty of Physical Activity and Sports Sciences (INEF)
Madrid, Madrid, Spain, 28040
Actively Recruiting
Research Team
S
Songxin Tang
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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