Bahawalpur

Myofascial pain syndrome MPS and radiculopathy are common musculoskeletal disorders that cause localized muscle pain, trigger points, stiffness, and nerve-related symptoms like radiating pain and weakness. These conditions often lead to postural problems and balance issues, including changes in the craniovertebral angle, which reflects the head and neck alignment. This trial aims to compare different physiotherapy treatments to improve this angle and reduce symptoms in people with MPS and radiculopathy, helping guide better clinical care. The study involves four groups receiving different physiotherapy approaches one group will have dry needling combined with myofascial release another will get trigger point therapy with stretching a third group will receive mobilizations with dry cupping therapy and the fourth group will undergo electrotherapy along with stretching and range of motion exercises. These treatments will be compared over time to assess their effects on posture, pain, function, and quality of life. Participants will attend scheduled physiotherapy sessions and undergo assessments before, during, and after the intervention, including measurements of craniovertebral angle, pain severity, balance, range of motion, and presence of trigger points. The study uses randomized assignment and triple masking to compare outcomes across groups over four weeks. The goal is to find which physiotherapy methods are most effective for improving posture and relieving symptoms in individuals with these conditions.

This research aims to evaluate and compare the effects of oral zinc sulfate and probiotic Lactobacillus rhamnosus GG supplementation in newborns with indirect hyperbilirubinemia who are receiving phototherapy. The study focuses on how these two treatments may help clear bilirubin and reduce the length of phototherapy in neonates. It is a phase 2 clinical trial sponsored by Quaid-e-Azam Medical College. Newborn participants will be randomly assigned to one of two groups one group will receive oral zinc sulfate syrup providing 5 mg of elemental zinc daily, and the other group will receive daily oral probiotic drops of Lactobacillus rhamnosus GG. Both treatments are given alongside standard phototherapy, following neonatal dosing guidelines. The study will monitor participants from the start of supplementation through the completion of phototherapy, which typically lasts 3 to 7 days. During the study, researchers will regularly measure bilirubin levels to assess the rate of decline while on phototherapy with the added supplement. The trial involves double masking to ensure unbiased results. Participants will be newborns under 7 days old with bilirubin levels appropriate for phototherapy according to NICE guidelines. The study includes parental consent and monitors safety and response throughout the treatment period, ending when phototherapy is completed.

Researchers are evaluating the effects of Jones technique and Ischemic compression technique on pain, range of motion, and disability in adults with cervicogenic headache, a type of headache caused by neck or cervical spine issues. Trigger points in muscles like the upper trapezius and sternocleidomastoid are thought to contribute to this headache type. This randomized clinical trial aims to compare these two treatment methods to find which may better reduce symptoms in patients aged 25 to 35 years. Participants will be randomly assigned to one of two groups. Group A will receive the Jones technique involving pressure on tender points combined with specific head and shoulder positioning, while Group B will receive ischemic compression therapy using sustained pressure on trigger points. Both groups will also receive baseline treatments including hot packs for 10 minutes, TENS for 15 minutes, and strengthening exercises for deep neck flexors. Treatments will be given twice weekly for six weeks. During the study, participants will be assessed using the Numeric Pain Rating Scale, Headache Disability Index, and Flexion Rotation Test at the start and after six weeks of treatment. Data will be analyzed to evaluate changes in pain, disability, and neck mobility. The study includes careful monitoring of symptoms and functional improvements over the treatment period to determine the impact of each technique.

Researchers are comparing two surgical methodsvolar locking plates and external fixatorsfor treating distal intra-articular radius fractures. The study aims to determine which approach offers better early functional recovery, fewer complications, and improved anatomical repair to help patients regain wrist function and return to daily life faster. Participants will be randomly assigned to one of two groups one group will receive volar locking plates using the modified Henrys volar technique with 2.4 mm locking compression plates, while the other group will be treated with an external fixator attached to metacarpal bones and radius using pins. These procedures will be evaluated to compare outcomes like operative time, blood loss, and wrist function. During the study, researchers will measure surgical details such as operation duration and blood loss, as well as wrist function over three months after surgery. This will help assess recovery progress and functional outcomes. The total participation period includes the surgery and follow-up assessments to monitor healing and wrist mobility improvements.