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Found 6 Actively Recruiting clinical trials

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Actively Recruiting

Myofascial pain syndrome (MPS) and radiculopathy are common musculoskeletal conditions that cause significant pain, stiffness, and difficulty with daily activities. Both conditions often lead to postural problems and balance issues, especially affecting the craniovertebral angle, which measures the alignment between the head and neck. This angle is frequently altered due to muscle imbalances and spinal changes, worsening symptoms and limiting movement. The study aims to compare different physiotherapy treatments to find the most effective ways to improve posture and reduce symptoms in people with MPS and radiculopathy. The study will involve four treatment groups: Group A will receive dry needling combined with manual myofascial release; Group B will have trigger point therapy plus stretching; Group C will get Maitland's mobilizations with dry cupping therapy; and Group D, the control group, will receive electrotherapy (TENS and ultrasound) along with stretching and range of motion exercises. These treatments will be applied according to recommended techniques and dosages, targeting improvements in craniovertebral angle and associated symptoms. Participants will undergo assessments before, during, and after treatment to measure changes in their craniovertebral angle, pain levels, balance, range of motion, and quality of life. The study will also monitor the presence of myofascial trigger points and functional ability. Researchers will analyze the data to determine which physiotherapy interventions provide the best outcomes, aiming to guide future treatment decisions and improve care for individuals affected by these conditions. The total participation will include multiple sessions and evaluations over the study period.

Age: 20Years - 40YearsAll GendersPhase Not Applicable
1 location
C

Actively Recruiting

Researchers are evaluating the effects of oral zinc sulfate and probiotic Lactobacillus rhamnosus GG supplementation in newborns with indirect hyperbilirubinemia who are receiving phototherapy. The study aims to compare how well these two supplements help clear bilirubin and reduce the duration of phototherapy in these neonates. This is a phase 2 trial focusing on term or near-term newborns within their first week of life. Participants will be randomly assigned to receive either oral zinc sulfate syrup, providing 5 mg of elemental zinc daily, or daily probiotic drops of Lactobacillus rhamnosus GG alongside standard phototherapy treatment. The supplementation occurs throughout the phototherapy period, which typically lasts 3 to 7 days. During the study, researchers will monitor bilirubin levels to measure the rate of decline from the start to the completion of phototherapy. They will also evaluate the total duration of phototherapy needed. Parents or guardians will provide informed consent, and infants will be assessed to ensure eligibility, including tolerance of oral feeds and absence of infections or other complications. The study includes safety monitoring throughout the treatment period.

Age: 0Days - 28DaysAll GendersPhase 2
1 location
E

Actively Recruiting

Healthy Volunteer

Cricket, a widely played team sport, involves complex skills developed over time, especially in bowling. Bowlers face a risk of shoulder injuries from imbalances between muscle groups. This research evaluates how the Ballistic Six program, which uses functional exercises mimicking overhead throwing motions, can improve strength, power, proprioception, kinesthesia, and endurance in rotator cuff muscles. It also examines the effects of blood flow restriction (BFR) training, which promotes muscle growth and strength by applying a tourniquet during rest periods to induce muscle hypoxia. Participants, male cricket players aged 18 to 25 with at least one year of experience, are randomly assigned to two groups in this randomized controlled trial. One group performs Ballistic Six plyometric exercises alone, while the other combines these exercises with blood flow restriction training. The intervention lasts eight weeks, with three weekly sessions of 20 to 30 minutes each. Monthly progress reports are recorded throughout the treatment period. Throughout the study, participants are assessed at the beginning and end using tests like the Kerlan Jobe Orthopedic Clinic (KJOC) Shoulder and Elbow Score, Closed Kinetic Chain Upper Extremity Stability Test, and Seated Medicine Ball Throw Test. Researchers monitor agility, strength, and functional ability to evaluate the effects of the training methods. The study aims to enhance performance and reduce injury risk in medium-pace cricket bowlers.

Age: 18Years - 25YearsMALEPhase Not Applicable
1 location
I

Actively Recruiting

Researchers are evaluating the effects of Jones technique and ischemic compression therapy on pain, range of motion, and disability in patients with cervicogenic headache, a type of headache caused by neck or cervical spine problems. This condition often causes pain that radiates from the neck to the head and is linked to trigger points in neck muscles. The study is a randomized clinical trial involving 32 patients aged 25 to 35 years, conducted at Bahawal Victoria Hospital, Bahawalpur, to compare these two physiotherapy treatments for myofascial trigger points in the upper trapezius and sternocleidomastoid muscles. Participants will be randomly split into two groups. Group A will receive the Jones technique, which involves applying pressure on tender points while moving the head and shoulder in specific ways, repeated three times per session. Group B will receive ischemic compression therapy, applying pressure to trigger points for 30 seconds to 1 minute, repeated 3 to 5 times per session. Both groups will have two treatment sessions per week for six weeks. Additionally, all patients will receive a baseline treatment including a 10-minute hot pack, 15 minutes of TENS therapy, and strengthening exercises for deep neck flexors. During the study, researchers will assess pain levels using the Numeric Pain Rating Scale, disability using the Headache Disability Index, and neck motion with the Flexion Rotation Test at six weeks. These measurements will help determine how each treatment affects symptoms and function. The study will analyze the data to identify significant differences between the two techniques, aiming to guide future therapy choices for cervicogenic headache.

Age: 25Years - 35YearsAll GendersPhase Not Applicable
1 location
U

Actively Recruiting

Researchers are evaluating the effects of therapeutic ultrasound and high intensity laser therapy on neuropathic pain, strength, and quality of life in patients with diabetic foot complications. This study focuses on people with diabetic peripheral neuropathy, a condition that causes nerve pain and weakness in the feet due to diabetes. The research aims to explore and compare how these two treatments improve symptoms and daily functioning, as current evidence about high intensity laser therapy is limited. The study compares two treatment groups: one receiving therapeutic ultrasound and routine physical therapy, and the other receiving high intensity laser therapy along with routine physical therapy. The ultrasound treatment uses a continuous 1 MHz frequency for 20 minutes per session, while the laser therapy uses a 905 nm super pulsed laser for 40 minutes per session. Both groups participate in therapy three days a week, including resistance training involving major leg and foot muscles, with 3-4 sets of 10-15 repetitions per exercise totaling 150 minutes weekly. Participants will be assessed over eight weeks using tools like the Michigan Neuropathy Screening Instrument and the Foot and Ankle Disability Index to measure neuropathic pain and foot-related disability. The study includes evaluations of pain levels, muscle strength, and quality of life. Researchers will monitor treatment effects throughout the study period, focusing on improvements in neuropathic symptoms and physical function in diabetic foot patients.

Age: 50Years - 75YearsAll GendersPhase Not Applicable
1 location
V

Actively Recruiting

Researchers are comparing two methods to treat distal intra-articular radius fractures: volar locking plates and external fixators. This study aims to determine which method leads to better early functional recovery, lower complication rates, and quicker return to daily activities, ultimately improving quality of life. Local data has shown mixed results, so this comparison seeks to provide clearer guidance for treatment choices. Participants will receive one of two treatments. One group will be treated with volar locking plates using the conventional modified Henry's volar technique with 2.4 mm locking compression plates to stabilize the distal radius fragments. The other group will receive an external fixator that is attached directly to the second or third metacarpal bone using 3-mm pins and to the radius using 4-mm Schanz pins. These procedures are designed to stabilize the fracture and support healing. During the study, researchers will measure operative time, blood loss, and wrist function over time, with wrist function being assessed at three months after treatment. Participants will be monitored for these outcomes to evaluate the effectiveness and safety of each treatment approach. This information will help identify which method best supports recovery and function after distal radius fractures.

Age: 20Years - 60YearsAll GendersPhase Not Applicable
1 location
Clinical trials in Bahawalpur | DecenTrialz