Sant Pere De Ribes

The registry focuses on patients with venous thromboembolism VTE, including those often excluded from typical clinical trials such as pregnant women, elderly patients, and those with serious health conditions. It aims to improve medical knowledge and patient care by collecting detailed data on these patients clinical status and treatment outcomes. The project also seeks to develop predictive scores to identify patients at higher risk of complications from thromboembolic disease. This observational registry collects extensive information on patients diagnosed with VTE, including details on coexisting conditions, antithrombotic treatment type, dose, and duration, as well as outcomes during the first three months of therapy. It captures data on VTE recurrences, bleeding complications, and deaths, providing insights into real-world treatment and patient management. Participants provide informed consent and are followed for at least three months to monitor clinical outcomes. The registry supports physicians by giving access to data on patients with similar profiles to help manage complex cases. The main outcomes measured include VTE events and complications over a three-year period, supporting ongoing improvements in patient care and risk assessment.

Researchers are evaluating two surgical techniques, Desarda and Lichtenstein, for repairing primary inguinal hernia. This study aims to find out if the Desarda technique, which does not use a mesh, leads to fewer postoperative complications compared to the commonly used Lichtenstein technique that involves mesh use. The trial is randomized and triple-blinded to compare these methods fairly. Participants will be randomly assigned to receive either the Desarda technique or the Lichtenstein technique for their hernia repair. Both are surgical procedures performed via an anterior approach, either as outpatient surgery or with elective admission. The trial monitors the rate of post-surgery complications within three months after the procedure. During the study, participants will be closely followed to assess any complications after surgery. Researchers will track postoperative outcomes for three months to compare safety and recovery between the two techniques. Participants will provide informed consent and meet specific eligibility requirements to join the trial, which is sponsored by Consorci Sanitari de lAlt Peneds i Garraf and is expected to continue until December 2030.

Researchers are comparing two methods of sealing peripheral venous catheters to see which reduces catheter obstruction more effectively. This randomized, double-blind clinical trial involves 3,450 hospitalized patients at the Hospital Residencia Sant Camil in Catalonia, Spain. The study aims to assess the percentage of catheters removed due to obstruction and also monitors related issues like phlebitis, bacteremia, extravasation, and catheter loss. Participants will be randomly assigned to one of two groups. One group will have catheters sealed with 3 mL of low-dose heparin Fibrillin 4, heparin 20UImL, while the other group will use 3 mL of 0.9% sodium chloride normal saline. The sealing process will be monitored throughout the hospital stay, which averages about 10 days. During the study, patients will be observed from the date of randomization until hospital discharge, approximately 10 days. Researchers will track catheter obstruction rates and record secondary outcomes such as catheter-associated phlebitis, bacteremia episodes, extravasation, and catheter loss. The trial includes rigorous safety monitoring and uses a triple-blind design to ensure unbiased assessment of results.

Researchers are investigating whether accelerated surgery for hip fracture patients with acute myocardial injury can reduce death rates within 90 days compared to the usual care. This international, multicenter, randomized controlled trial also evaluates secondary outcomes like walking ability, time to first mobilization, major complications including heart attacks and stroke, delirium, pain, length of hospital stay, and quality of life. The trial compares two approaches one group receives rapid medical clearance and surgery within 6 hours of meeting eligibility, while the other group undergoes hip fracture repair following standard hospital procedures. Surgery and care are performed according to institutional guidelines, with the accelerated group targeting quick operating room arrival. Participants will be monitored for 90 days after randomization. Researchers will assess survival, walking independence, major cardiovascular complications, delirium episodes, pain levels, and hospital discharge timing. This includes tracking events like myocardial infarction, heart failure, and stroke. The study aims to gather comprehensive data on safety and recovery outcomes related to timing of surgery in this patient group.

Researchers are evaluating the usefulness of the NECPAL scale in identifying patients admitted to the Intensive Care Unit ICU who are at higher risk of dying within 90 days after ICU admission. This observational study focuses on adults aged 75 years and older admitted to the ICU, aiming to assess mortality risk using this specific tool. Participants are grouped based on whether they have a positive result on the NECPAL scale, which is being observed to see if it is associated with higher mortality. The study does not involve treatment interventions but focuses on monitoring and evaluating outcomes related to the NECPAL scale results. During the study, participants vital status will be followed from ICU admission up to 90 days to measure mortality rates. Researchers will collect relevant data to understand how well the NECPAL scale predicts death risk. Participants or their legal representatives provide informed consent, and those who die within 24 hours of ICU admission are excluded from the study.

Researchers are evaluating cognitive performance in the oldest-old population, those aged 80 years and above, as current neuropsychological tests are not well adapted for this age group. This observational study aims to establish normal limits for 18 neuropsychological tests to improve diagnostic evaluations for this population. The research is sponsored by Consorci Sanitari de lAlt Peneds i Garraf and involves subjects without cognitive-affecting pathologies. The study will include 120 non-institutionalized participants aged 80 or older from the Comarca del Garraf area, divided into four age groups 80-84, 85-89, 90-94, and 95 or more. Participants will undergo 18 neuropsychological tests typically used in memory clinics. Test results will be adjusted for age and education level using linear regression, and normal limits will be defined by percentiles. Participants will be evaluated at a Memory Clinic Unit after enrollment, where cognitive performance will be assessed in about 60 minutes. Researchers will collect data through these tests to define normal cognitive function ranges for this age group. The study excludes individuals with certain mental illnesses, central nervous system diseases, severe sensory deficits, or dementia. Participation involves attending scheduled assessments and cooperating with test procedures until study completion in March 2026.

Researchers are evaluating the safety of remote consultations, including video and telephone calls, compared to traditional face-to-face visits for patients followed up in a hospital setting. This randomized-controlled trial involves 2136 patients and aims to determine if remote consultations lead to a similar rate of complications related to the underlying diseases. The study excludes patients who require physical exams or have impairments affecting communication, as well as those involved in other clinical trials with experimental treatments. Participants will be randomly assigned to one of three groups face-to-face consultations, telephone consultations, or video consultations. In the face-to-face group, patients will have in-person appointments with limited phone interactions allowed. For the remote consultation groups, patients will receive reminders and either wait for a phone call or join a virtual waiting room for video calls. Physicians schedule visits as needed, including baseline, intermediate, and final visits within approximately one year. During the study, participants will undergo at least three visits, including initial screening, follow-ups, and a final visit around 12 months after enrollment. Researchers will monitor the frequency of disease complications, treatment adverse reactions, hospitalizations, unscheduled medical contacts, and healthcare costs. They will also assess the usability of the video system and satisfaction of both patients and health professionals. The study observes patients outcomes and safety throughout this period.

Researchers are developing a predictive model to identify elderly patients aged 75 or older who have the highest risk of mortality when admitted to an intensive care unit ICU with critical illness. This observational study focuses on patients admitted from the Emergency Department and aims to improve understanding of factors that influence survival outcomes in this vulnerable population. The study involves analyzing laboratory biomarker results as predictors of mortality. Patients are observed without any interventional treatment assigned by the study, and data collection occurs during their ICU stay. The primary outcome measured is mortality at 90 days after ICU admission. Participants will provide informed consent, or a legal representative will do so if necessary. Researchers will collect clinical and laboratory data, monitor patient status during ICU admission, and follow up to assess survival at 90 days. The study excludes patients transferred from hospital wards, those who die within 24 hours of ICU admission, and those admitted to Step-Down Units or meeting certain medical criteria. Participation lasts through the ICU stay and follow-up period until the 90-day mortality outcome is recorded.

Researchers are studying how often amyloidosis occurs in patients who are undergoing trauma surgery. This observational study is designed to identify the presence of amyloidosis using a red flags tool among adults and elderly patients who are on a waiting list for scheduled trauma surgery and meet specific risk criteria. The study is sponsored by Consorci Sanitari de lAlt Peneds i Garraf and aims to provide important insights into the frequency of this condition in the trauma surgery population. The study involves patients who are scheduled for trauma surgery and who meet at least one red flag criterion, such as age over 65, possible family history of amyloidosis, or certain cardiac, nerve, kidney, or liver conditions without clear causes. Participants will be observed and evaluated for amyloidosis through clinical assessments and necessary tests during their pre-surgery evaluations. No experimental drugs or interventions are administered, as this is an observational study. Participants will be involved in evaluations necessary to detect amyloidosis, including clinical assessments and review of medical history related to heart, nerve, kidney, and liver health. The main outcome measured is the presence of amyloidosis within one month. Participants need to be able to cooperate with these evaluations and provide informed consent. The study does not involve any treatment and focuses on data collection and monitoring during the pre-surgery period and shortly after.