Sant Pere De Ribes

Researchers are collecting detailed information about patients with venous thromboembolism (VTE), which includes blood clots in veins such as deep-vein thrombosis and pulmonary embolism. The project aims to improve doctors' understanding of VTE, especially in patients often excluded from clinical trials, like pregnant women, elderly individuals, cancer patients, and those with other complex health issues. The goal is to reduce deaths, clot recurrence, bleeding problems, and artery-related events by sharing this knowledge widely. The study involves gathering extensive data on each patient's health status, treatments, and outcomes during the first three months of therapy. This registry is available online to help doctors quickly find information on patients with similar medical profiles and make informed decisions about managing high-risk individuals. There are no specific interventions being tested; instead, the focus is on collecting real-world patient data. Participants provide informed consent and are followed for at least three years to monitor for new clot events and complications. Researchers track recurrences of VTE, bleeding episodes, and deaths, aiming to create tools that predict which patients are most at risk for problems. This ongoing data collection supports improving care and guiding treatment decisions for diverse patient groups over time.

Researchers are evaluating whether the Desarda surgical technique is better than the Lichtenstein technique for repairing primary inguinal hernias, focusing on the rate of complications after surgery. The Desarda method avoids using a mesh, while the Lichtenstein method uses a mesh to repair the hernia. This randomized controlled trial compares these two approaches to determine which yields fewer postoperative issues within three months. Participants will be randomly assigned to receive either the Desarda tissue technique, which repairs the hernia without mesh, or the Lichtenstein technique, which involves mesh placement during surgery. Both methods are performed through an anterior approach and can be done as outpatient procedures or with elective admission, depending on the patient's needs. During the study, participants will be monitored for any complications occurring up to three months after surgery. Researchers will assess recovery and safety outcomes related to the surgical techniques used. Patients must provide informed consent and meet specific eligibility criteria to participate in the trial, which focuses on adult patients with primary inguinal hernias and certain health requirements.

Researchers are conducting a randomized, double-blind clinical trial to compare the effectiveness of sealing peripheral venous catheters with low-dose heparin versus normal saline. The study involves 3,450 patients hospitalized at the Hospital Residencia Sant Camil in Catalonia, Spain. The main focus is to measure the percentage of catheters removed due to obstruction in each treatment group, with additional monitoring of complications such as catheter-associated phlebitis, bacteremia, extravasation, and catheter loss. The trial aims to determine if one method is superior in preventing catheter obstruction. Participants will be randomly assigned to have their catheters sealed either with 3 mL of low-dose heparin (20 units/mL) or with 3 mL of 0.9% sodium chloride (normal saline). Catheter sealing will be performed during the hospital stay, with treatments applied to peripheral venous lines used for discontinuous treatment. The study does not involve emergency medical situations for catheter placement. During the study, patients will be monitored from the time of randomization until hospital discharge, averaging 10 days. Researchers will track the occurrence of catheter obstruction and related complications. Data collection includes the number of catheter removals due to obstruction and other catheter-associated adverse events. Patient safety and catheter function will be closely observed throughout the hospitalization period.

The HIP ATTACK-2 trial is a multicentre, international, parallel group randomized controlled trial to determine whether accelerated surgery for hip fracture in patients with acute myocardial injury is superior to standard care in reducing death at 90 days after randomization. The trial will also assess secondary outcomes at 90 days after randomization: inability to independently walk 3 metres, time to first mobilization (first standing and first full weight bear), composite and individual assessment of major complications (e.g., mortality, non-fatal myocardial infarction, acute congestive heart failure, and stroke), delirium, length of stay, pain, and quality of life.

This research aims to evaluate the usefulness of the NECPAL scale in identifying Intensive Care Unit (ICU) patients who are at a higher risk of dying within 90 days after ICU admission. The study focuses on patients aged 75 years or older admitted to the ICU, assessing whether a positive NECPAL result is associated with increased mortality. This is an observational evaluation involving patients with acute disease conditions requiring critical care. Participants are grouped based on their NECPAL scale results, specifically those who test positive on the scale. The study observes these ICU patients from the point of admission onward, with no additional interventions described beyond standard ICU care. The study tracks outcomes over a 90-day period following ICU admission to assess mortality. During the study, patients will be monitored for vital status and survival up to 90 days from their ICU entry. Researchers will collect data on mortality as the primary outcome measure. The total participation duration for each patient is 90 days, during which their survival status will be closely followed and recorded to evaluate the association between NECPAL positivity and mortality risk.

Researchers are studying cognitive performance in people over 80 years old who live outside of institutions. They aim to establish normal ranges for 18 common neuropsychological tests used in Memory Clinics, as current tests may not be well-suited for this oldest-old population. The study will help improve how cognitive abilities are assessed in this age group. The study will enroll 120 participants aged 80 and older, divided into four age groups: 80-84, 85-89, 90-94, and 95 or older. Participants will be randomly selected from five Primary Care Centers in the Comarca del Garraf region. Each person will complete 18 neuropsychological tests, with results adjusted for age and education level. Participants will visit the Memory Clinic Unit for cognitive testing, which lasts about 60 minutes. Researchers will measure cognitive performance using the test scores and define normal limits based on percentiles. The study excludes people with severe mental illness, recent hospitalizations, major neurological diseases, or dementia. This study focuses on people who can read and write sufficiently and are able to travel to the study site.

Researchers are evaluating the safety of remote consultations, including video and telephone visits, compared to traditional face-to-face consultations for patients with various clinical conditions usually followed in a secondary hospital. This randomized controlled trial aims to determine if remote consultations result in a similar frequency of complications of the underlying disease over a 12-month period, including any adverse reactions to treatment. The study includes adults and children who can participate in remote follow-up without requiring physical examinations and who have the necessary technology and skills for video consultations. Participants will be randomly assigned to one of three groups: the control group with face-to-face appointments, or one of two remote consultation groups using telephone or video calls. In the control group, face-to-face visits are the standard, with limited phone call interactions allowed. For remote consultations, patients will receive reminders and will either wait for a scheduled phone call or join a virtual waiting room for video calls. Physicians will schedule at least three visits, including a baseline screening visit, intermediate visits based on patient needs, and a final visit around 12 months after enrollment or sooner if necessary. During the study, participants will be regularly evaluated through these scheduled visits, and physicians can adjust appointments as needed. The main outcome measured is the occurrence of disease complications within 12 months. Researchers will track safety through monitoring complications and adherence to the assigned consultation method. The study will analyze results from participants who complete the study as planned without unapproved changes in consultation modes.

Researchers are working to create a predictive model to identify elderly patients aged 75 or older who have the highest risk of death when admitted to an intensive care unit (ICU) with critical illness. The goal is to use patient data to better understand and predict outcomes in this vulnerable population. Participants admitted to the ICU from the Emergency Department will have laboratory biomarker results analyzed. These biomarker results will be studied as potential predictors of mortality. The study focuses on patients aged 75 or older and does not include those transferred from hospital wards or those admitted to step-down units. The study excludes patients who die within 24 hours of ICU admission and those needing ICU care for specific urgent interventions before arrival. During the study, researchers will collect relevant data and analyze laboratory biomarkers to assess their ability to predict mortality by day 90. Consent will be obtained from participants or their legal representatives. The study involves contacting informants if needed and monitoring outcomes over time to develop the predictive model for mortality in this critical care setting.

This research aims to find out how often amyloidosis occurs in patients who are scheduled for trauma surgery. The study focuses on adults who show certain risk signs, or "red flags," related to amyloidosis, such as older age, family history, and specific heart, nerve, kidney, or liver problems. The goal is to better understand the presence of amyloidosis in this group of patients. Participants will be patients preparing for trauma surgery who meet at least one of the red flag criteria. These criteria include being over 65 years old, having a possible family history of amyloidosis, or having particular heart conditions like aortic stenosis or abnormal heart rhythms. Other factors include a history of nerve damage, unexplained kidney disease, or unexplained liver disease. The study involves undergoing trauma surgery as part of their medical care. During the study, researchers will monitor the participants for amyloidosis over a one-month period. Participants must be able to cooperate with the evaluations and provide informed consent. The main outcome measured is the presence of amyloidosis one month after surgery. Those previously diagnosed with amyloidosis will not be included in the study.