Hama

Researchers are investigating the use of injectable platelet-rich fibrin i-PRF to potentially speed up orthodontic tooth movement, specifically focusing on the leveling and alignment of maxillary incisors. The study responds to limited evidence from previous research on PRF and orthodontic treatment time reduction. The trial aims to evaluate i-PRFs effect during comprehensive orthodontic therapy in patients with severe upper incisor irregularity. Participants will be randomly assigned to one of two groups. One group will receive a 0.9 ml injection of i-PRF after extraction of the first premolar as part of their orthodontic treatment. The other group will undergo traditional orthodontic treatment and receive a placebo injection after the same tooth extraction. The study is single-blinded and randomized to compare these two approaches. During the study, participants will undergo orthodontic treatment with regular follow-ups over several months, where the rate of tooth leveling and alignment will be measured at one, two, and six months. Researchers will monitor changes in tooth position and overall oral health throughout the treatment period. The total involvement duration corresponds to the orthodontic treatment timeline, with safety and treatment progress carefully assessed.

This research aims to evaluate the effectiveness of micro-osteoperforations MOPs in speeding up tooth movement during orthodontic treatment for adults with moderate crowding of their lower front teeth. The study focuses on patients using clear aligners, a popular cosmetic alternative to traditional braces. It also assesses patients pain levels and satisfaction with the treatment, addressing a common concern for those undergoing orthodontic care. Participants will be randomly assigned to one of two groups. The first group will receive traditional clear aligner treatment combined with the micro-osteoperforations technique, where small perforations are made in the bone of the lower jaw using a special drill to potentially accelerate tooth movement. The second group will receive the traditional clear aligner treatment alone without any surgical procedure. Aligners in both groups will be changed based on fit. During the study, researchers will measure changes in dental alignment using Littles Index of Irregularity at various times, including before treatment and up to five months after starting. They will also monitor overall treatment time, pain levels shortly after treatment begins, and patient satisfaction with the procedure and ease of use. The study includes regular assessments to track progress and gather patient feedback, helping to understand the impact of the micro-osteoperforations technique during clear aligner therapy.

This research aims to evaluate the effectiveness of clear aligners combined with intermaxillary elastics in treating patients aged 15 to 20 years who have Class II division 1 malocclusion with a mild increase in overjet. The study compares skeletal, dental, and soft tissue changes caused by this treatment against those seen with traditional fixed appliance therapy. It seeks to provide a detailed assessment of how these two approaches impact the correction of this specific type of malocclusion. Participants are divided into two groups one will receive clear aligners applied to both upper and lower arches along with Class II elastics worn from a precision-cut hook on the maxillary aligner to a button on the mandibular first molar. The other group will undergo traditional fixed multibracket appliance treatment with elastics attached from canine bracket hooks to the lower first molar after leveling and alignment are complete. Treatments will continue until a normal overjet and Class I canine relationship are achieved, expected within 4 to 6 months for the clear aligner group and up to 12 months for the fixed appliance group. During the study, participants will be monitored through various measurements including changes in angles and lengths related to jaw and teeth positioning, such as the SNA, SNB, ANB, and others, taken before treatment starts and once the targeted dental relationships are established. These evaluations aim to track the structural changes in the skeleton and teeth over time. The study uses a randomized design and single masking, and participation duration varies depending on the treatment group and progress toward treatment goals.

This research aims to evaluate the effectiveness of clear plates in treating patients with skeletal class II malocclusion characterized by a retracted lower jaw. The study compares the skeletal, dental, and soft tissue changes achieved by a Modified Twin-Block Appliance with Clear Plates against the Traditional Twin-Block Appliance. Both treatments focus on correcting this specific jaw misalignment in children aged 10.5 to 13 years with mixed dentition. Participants are randomly assigned to one of two groups one will use the Modified Twin-Block Appliance with Clear Plates, and the other will use the Traditional Twin-Block Appliance. Both devices are applied to the upper and lower dental arches and worn for 17 hours daily. The treatment period is expected to last 6 to 9 months, aiming to achieve a normal overjet and Class I canine relationships. During the study, changes in several measures will be monitored, including the SNA and SNB angles, mandibular length, overjet, and the vertical position of incisors. These measurements will be taken before treatment and once the desired dental relationships are achieved. The study ensures participants have no prior orthodontic treatment and monitors their dental and skeletal development closely to assess treatment outcomes.