Isparta Merkez

Researchers are studying adults aged 18 to 80 who have experienced acute traumatic peripheral nerve injuries in their upper limbs, such as injuries to the median, ulnar, or radial nerves. The study aims to evaluate how these surgically treated nerve injuries affect sensory and motor functions, overall functional status, and quality of life over the long term. This research focuses on understanding the outcomes of nerve damage due to trauma and how it impacts patients' daily lives. Participants will undergo standard clinical and functional assessments to evaluate the extent of their peripheral nerve injuries. These evaluations include motor, sensory, and functional outcome measures without being assigned to specific therapeutic interventions. The study collects detailed information on nerve injury outcomes following either surgical or conservative management. During the study, participants will be assessed using tools like the Michigan Hand Outcomes Questionnaire, which measures functional outcomes of the injured hand at six months after injury. Researchers will monitor sensory and motor recovery, functional status, and quality of life throughout the study. Participants must be able to complete clinical and functional evaluations and provide informed consent. The total involvement duration and follow-up schedules are defined to track the long-term effects of nerve injuries.

Researchers are evaluating the effect of a triple therapy inhaler called BGF MDI containing budesonide, glycopyrronium, and formoterol fumarate compared with a dual therapy inhaler called GFF MDI containing glycopyrronium and formoterol fumarate in people with Chronic Obstructive Pulmonary Disease (COPD) who have a higher risk of heart and lung problems. This Phase III randomized, double-blind, parallel group study takes place at multiple centers and focuses on cardiopulmonary outcomes in these patients. Participants receive either the BGF MDI 320/14.4/9.6 micrograms twice daily or the GFF MDI 14.4/9.6 micrograms twice daily. The treatments are inhaled using metered dose inhalers. The study compares these two therapies over time to see how they affect the time until the first severe heart or lung event occurs. The study design ensures that neither participants nor researchers know which treatment is given to reduce bias. During the study, participants will have regular visits to the study site or virtual visits to complete assessments. Researchers will monitor lung function, symptoms, and blood tests, including blood eosinophil counts and COPD assessment test scores. The main outcome measured is the time to the first severe cardiac or COPD event, with follow-up lasting up to three years. Safety and adherence to treatment will also be closely observed throughout the study period.

This research aims to evaluate the safety, performance, and usability of Occlutech accessory medical devices used in cardiac implant procedures. It is an international, multicenter, non-randomized, non-invasive registry study focusing on devices such as the Occlutech Delivery Set (ODS), Occlutech Pistol Pusher (OPP), Occlutech Occlusions-Pusher (OOP), and Occlutech Sizing Balloon (OSB). The study collects data through investigator-completed surveys to monitor device-related outcomes during and after catheter-based cardiac implant interventions. The study involves the use of the specified Occlutech accessory devices by experienced physicians skilled in cardiac catheterization and interventional operations. Investigators complete detailed questionnaires assessing the success of implantation procedures, any adverse events occurring during or after the procedures, user harm related to the accessories, and any device deficiencies. The surveys also evaluate performance, usability, and compatibility of the accessories with other devices. Participants are treated following the implants' and accessories' instructions for use and standard clinical practice. Participants' involvement includes undergoing implantation procedures with these accessory devices, after which investigators collect data via surveys. The study monitors safety events over six months, including any adverse outcomes linked to the accessories or procedures. The collected information helps assess the devices' safety profile and practical use in real-world clinical settings. The total duration of monitoring and follow-up is six months per participant to capture both immediate and longer-term effects.

This study investigates how different recreational exercises—Pilates, swimming, and walking—affect muscle strength and balance in women aged 40 to 60 who are at risk of developing osteoporosis. The researchers aim to compare the effectiveness of these exercises in improving muscle strength and balance, testing hypotheses that Pilates and swimming may be more beneficial than walking for this population. Participants are divided randomly into three groups, each performing one type of exercise three times a week for 12 weeks. The Pilates group engages in mat Pilates sessions led by a certified instructor, including warm-up, main exercises, and cool-down. The swimming group performs moderate-intensity swimming with warm-up, main swimming sets, and cool-down, while the walking group completes brisk walking sessions with gradual increases in speed over the study period. Exercise intensity is monitored, and participants with less than 80% attendance are excluded from analysis. Throughout the study, researchers assess muscle strength in the hands and trunk and evaluate balance using the Berg Balance Scale and computerized posturography both at the beginning and end of the 12-week intervention. Participation rates and exercise adherence are tracked to ensure compliance, and the outcomes will help understand how these common recreational activities contribute to muscle strength and balance in women at osteoporosis risk.

This research aims to evaluate how game activity and stress ball use affect anxiety and vital signs before surgery in patients undergoing total knee arthroplasty. The study focuses on reducing preoperative anxiety, which is known to cause physiological and psychological reactions that may affect surgery satisfaction, success, and complications. About 30% of patients having this surgery experience psychological distress beforehand. Various low-cost, easy-to-apply methods like music, videos, massage, and gaming activities have been used to manage anxiety in adults, with game-based approaches more common in children. Stress balls, though less studied, may also help manage anxiety by providing a different focus for attention. Participants will be divided into three groups: one will play a researcher-chosen game in their patient room, another will use a stress ball for 15 minutes, and a control group will receive no intervention. These methods are simple, cost-effective, and do not burden patients. The study collects data using the State Anxiety Inventory, pain level, vital signs, and descriptive forms to assess the effects of these interventions. Participants will have measurements taken at their first encounter and then again 15 minutes after intervention for those receiving it, or one hour after the first measurement for controls. The assessments include anxiety levels, pain, temperature, blood pressure, heart rate, oxygen saturation, and respiratory rate. The study involves adults over 18 who have passed cognitive testing and meet other criteria, with attention to vital sign stability and psychological status throughout the process.

Researchers are evaluating the effects of oral care with sodium bicarbonate, saline, and black mulberry syrup on oral mucositis in children aged 6 to 18 years who are receiving chemotherapy. Oral mucositis is a common complication of cancer treatment that can affect nutrition, daily activities, and quality of life, and it may impact the ability to continue scheduled therapy. This randomized controlled experimental study aims to compare these three oral care methods to understand their influence on mucositis levels in this pediatric population. Participants are randomly assigned to one of three groups. The control group receives routine oral care with sodium bicarbonate, while the two experimental groups receive routine care plus either saline or black mulberry syrup as a 5 ml mouthwash. Oral care is administered four times daily for 14 days in all groups. The study uses established assessment scales to evaluate mucositis severity and collects neutrophil counts at multiple time points during the study. Children will be assessed on days 1, 2, 4, 8, and 16 using the International Child Mucositis Evaluation Scale and the World Health Organization Mucositis Classification. Data on neutrophil counts and patient information are also collected. The study monitors oral mucositis levels and the effects of the different oral care methods over a 16-day period during chemotherapy treatment.

Researchers are comparing two teaching methods, Flipped Classroom (FC) and Flip-Jigsaw, to see how they affect learning, motivation, and engagement among third-year physiotherapy undergraduate students in a public health theory course. The study focuses on understanding whether the hybrid Flip-Jigsaw model, which combines video-based pre-learning and peer teaching, provides different benefits compared to the FC model that uses pre-class videos followed by instructor-led discussions. This investigation aims to fill a gap in knowledge about the effectiveness of Flip-Jigsaw in physiotherapy education. The study involves two groups of students using the same video lectures for content. The FC group participates in instructor-led discussions during class, while the Flip-Jigsaw group engages in structured peer teaching activities where students learn subtopics in expert groups and teach them in master groups. This design includes role-based accountability and teamwork aspects to enhance learning. Both groups complete pre- and post-tests, and motivation and engagement are assessed through surveys and participation measures. Participants attend all lectures and complete knowledge tests before and immediately after the 7-week intervention. Researchers measure changes in theoretical knowledge, motivation, and class engagement. They also conduct qualitative interviews and use blinded assessors for practical exams to ensure objectivity. The total study participation lasts 7 weeks, during which students' learning outcomes and classroom involvement are closely monitored and compared between the two teaching methods.

This research aims to explore the relationship between how strongly patients with knee osteoarthritis (OA) feel bodily sensations, their psychological and functional status, and the level of pain they experience. It focuses on patients aged 40 to 84 who have had knee OA and pain for at least six months. The study addresses gaps in understanding how these factors connect, which may help guide evaluation and treatment programs for knee OA. Participants will complete several questionnaires to assess different aspects of their condition. These include the Somatosensory Amplification Scale to measure sensitivity to bodily sensations, the Tampa Kinesiophobia Scale to assess fear of movement, the Visual Analog Scale for pain levels, the Beck Depression Inventory for depression symptoms, and the Western Ontario and McMaster Universities Arthritis Index to evaluate functional status. Sociodemographic information such as age, gender, height, weight, body mass index, education level, and marital status will also be collected. During the study, participants will be evaluated using these survey tools within a two-week period. Researchers will analyze the data to find correlations between somatosensory amplification, psychological and functional status, and pain levels. Statistical methods will be used to understand how these factors relate, with the goal of improving understanding of knee OA. The study will carefully monitor participants' responses to ensure accuracy and validity of the findings.

Researchers are evaluating a Peer Leadership Program to study its impact on nursing students' empathic self-efficacy, social self-efficacy, and youth leadership traits. This quasi-experimental study involves nursing students from the second, third, and fourth years at Sfcleyman Demirel University's Faculty of Health Sciences during the 2024-2025 academic year. The program aims to enhance communication, empathy, social motivation, and leadership skills among peer mentors. The study spans six weeks, during which peer mentors participate in weekly sessions that include training on communication techniques, interview methods, empathic approaches, social motivation, and leader-member interaction. Sessions also involve sharing postcasts related to these topics. The program culminates in a group presentation based on the theme "Nursing and Society," where mentors and mentees collaborate creatively through compositions, poems, posters, presentations, or role plays. Participants complete assessments before the first session and after the final session to measure changes in their empathic and social self-efficacy as well as leadership characteristics. Socio-demographic data are also collected. The study monitors these outcomes to understand the program's effects on peer mentors over the six-week period.

Researchers are evaluating the effects of yoga and Whole Body Vibration Training on pelvic floor muscle strength, urinary symptoms, and quality of life related to urinary incontinence in women with stress urinary incontinence (SUI) or mixed urinary incontinence with a predominant SUI component. The study focuses on women aged 20 to 60 who have not received physical therapy for urinary incontinence in the past three months. The study lasts for 6 weeks and compares three groups: one practicing yoga three times a week for 45 minutes with specific poses, another undergoing Whole Body Vibration Training for 40 to 45 minutes including warm-up, active, and cooling phases, and a home exercise group performing daily pelvic floor muscle training with slow and fast contractions in various positions. Each intervention is designed to assess its impact on urinary incontinence symptoms. Participants will be monitored through several assessments at the 6-week mark, including pelvic floor muscle strength tests, urinary symptom severity scales, incontinence impact questionnaires, and a 1-hour pad test. These evaluations will help measure treatment effects on muscle strength and quality of life related to urinary incontinence. Safety and adherence will also be observed during the study period.