Chronic viral coinfections differentially affect the likelihood of developing long COVID.
Michael J Peluso, Tyler-Marie Deveau, Sadie E Munter...
https://pubmed.ncbi.nlm.nih.gov/36454631/Actively Recruiting
Led by University of California, San Francisco · Updated on 2026-07-23
800
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are investigating the long-term effects of COVID-19 infection in people who have recovered from the acute illness. This observational study focuses on understanding how the immune system and other bodily responses vary among individuals over time. It also examines how factors like age, gender, and race may influence these long-term outcomes after SARS-CoV-2 infection. Participants who have recovered from COVID-19 are followed at San Francisco General Hospital starting with a baseline visit, then monthly visits for 3 months, and subsequently every 3 months for up to 2 years. At each visit, detailed interviews are conducted along with saliva and blood sample collections. The study aims to create a specimen bank of samples linked to well-documented clinical data for further research. During the study, participants undergo interviews and sample collections to measure immune activation, inflammation, and other health changes over time. Demographic details and hospitalization history are recorded at baseline. Follow-up visits last about 20 to 40 minutes while the initial visit takes approximately 90 minutes. Personal identifiers are removed from samples to protect privacy. The study monitors outcomes related to long COVID up to 24 months after infection.
CONDITIONS
Long-term Impact of Infection With Novel Coronavirus (COVID-19)
E
Emily A Fehrman, MPH
M
Michael J Peluso, MD
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University of California, San Francisco
Lead Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 2 years
Participants attend a baseline visit, monthly visits for 3 months, then every 3 months for up to 2 years. Visits include interviews, saliva collection, and blood draws to study long-term effects of COVID-19.
Baseline visit, monthly visits for 3 months, then visits every 3 months
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Michael J Peluso, Tyler-Marie Deveau, Sadie E Munter...
https://pubmed.ncbi.nlm.nih.gov/36454631/University of California, San Francisco
Lead Sponsor