Actively Recruiting

All Genders
NCT03492060

Longitudinal Study of Neurogenetic Disorders

Led by Columbia University · Updated on 2025-10-27

1000

Participants Needed

1

Research Sites

650 weeks

Total Duration

On this page

Sponsors

C

Columbia University

Lead Sponsor

S

Simons Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to analyze patterns in individuals with hnRNP (and other) genetic variants, including their neurological comorbidities, other medical problems and any treatment. The investigators will maintain an ongoing database of medical data that is otherwise being collected for routine medical care. The investigators will also collect data prospectively in the form of questionnaires, neuropsychological assessments, motor assessments, and electroencephalography to examine the landscape of deleterious variants in these genes.

CONDITIONS

Official Title

Longitudinal Study of Neurogenetic Disorders

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Individuals must have had whole genome/exome sequencing and have a confirmed variant in any gene.
Not Eligible

You will not qualify if you...

  • Subjects who cannot provide genetic confirmation of a predicted deleterious variant in any gene.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Columbia University Irving Medical Center

New York, New York, United States, 10032

Actively Recruiting

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Research Team

J

Jennifer M. Bain, MD, PhD

CONTACT

J

Joanna Feng

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Longitudinal Study of Neurogenetic Disorders | DecenTrialz