Actively Recruiting

Age: 18Years +
All Genders
ID07287891

Lost in the Labyrinth: Predicting Central Neurological Causes of Vertigo Dizziness and Unsteadiness in the Emergency Department A Multicentre Cross-sectional Observational Study

Led by Fondazione IRCCS Policlinico San Matteo di Pavia ยท Updated on 2025-12-17

825

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate how well an examination method performed by emergency department (ED) physicians can identify central neurological causes of symptoms like vertigo, dizziness, and unsteadiness. The study will also explore factors that predict when these symptoms have a central cause. By doing this, it hopes to reduce misdiagnoses and lower the need for unnecessary neuroimaging tests, which can increase costs and hospital stays. Participants include patients who come to the ED with vertigo, dizziness, or unsteadiness. During their ED visit, trained emergency physicians or residents will perform a thorough bedside examination focused on vertigo. This study is observational and will monitor patients over a period of up to 36 months to assess how accurate the bedside examination is and how often neuroimaging tests are performed. Participants will undergo the bedside examination during their ED visit, and researchers will collect data on the examination's accuracy measured by the area under the curve (AUC) over 36 months. They will also track predictors of true positive cases and the number of neuroimaging tests given. The study focuses on improving diagnosis and patient management without introducing new treatments. Participation requires giving consent and involves observation during routine care.

CONDITIONS

Brief Title

Lost in the Labyrinth: Predicting Central Neurological Causes of Vertigo Dizziness and Unsteadiness in the Emergency Department. A Multicentre Cross-sectional Observational Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients presenting at the ED with vertigo, dizziness or unsteadiness
  • 18 years of age or older
  • Patients able to give their consent
Not Eligible

You will not qualify if you...

  • Patients with dementia
  • Bedridden patients (for causes other than the current symptoms)
  • Patients with obvious neurological findings presenting with vertigo but with suspected stroke at triage

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person) at the Emergency Department

Diagnostic Evaluation

Duration - Single visit

Participants undergo a bedside examination of vertigo performed by trained emergency physicians during their Emergency Department visit.

1 visit (in-person) at the Emergency Department

Long-term Monitoring

Duration - Up to 36 months

Participants are observed for up to 36 months to assess outcomes related to the bedside examination algorithm and neuroimaging tests.

Follow-up assessments as per clinical care; no scheduled trial visits

Trial Site Locations

Total: 1 location

1

SC Pronto Soccorso e Medicina d'Urgenza, Fondazione IRCCS Policlinico San Matteo

Pavia, Pavia, Italy, 27100

Actively Recruiting

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Research Team

M

Marco Bonzano, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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