Actively Recruiting
Lung Recruitment Assessed by 2D/3D-EIT and R/I Ratio in Acute Respiratory Failure Patients With Mechanical Ventilation
Led by Peking Union Medical College Hospital · Updated on 2026-01-30
50
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this observational study is to assess the differences and consistency in evaluating lung recruitment potential between the recruitment-to-inflation ratio (R/I ratio) and three-dimensional electrical impedance tomography (3D-EIT) and two-dimensional EIT (2D-EIT) in mechanically ventilated patients with acute respiratory failure. The main questions it aims to answer is: Are the lung recruitment potentials predicted by 3D-EIT, 2D-EIT and the R/I ratio consistent? Participants will: Undergo a standardized PEEP titration protocol with synchronized EIT monitoring; Have R/I ratios measured at high and low PEEP levels.
CONDITIONS
Official Title
Lung Recruitment Assessed by 2D/3D-EIT and R/I Ratio in Acute Respiratory Failure Patients With Mechanical Ventilation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Mechanically ventilated patients under sedation and analgesia with no spontaneous breathing.
- Oxygenation index less than 300 mmHg.
- Patients clinically judged by the attending doctor to require PEEP titration.
You will not qualify if you...
- Under 18 years of age.
- Pregnancy.
- Contraindications for EIT examination such as implanted cardioverter defibrillator, implantable pumps, chest wounds limiting electrode belt placement, severe thoracic deformity, and others.
- No informed consent obtained.
- Hemodynamic instability with intolerance to high PEEP levels as determined by the attending doctor.
- High-risk conditions like pneumothorax, mediastinal emphysema, or similar as determined by the attending doctor.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences
Beijing, Beijing Municipality, China, 100730
Actively Recruiting
Research Team
H
Huaiwu He
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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