Assessing Lung Recruitment Using 2D3D Electrical Impedance Tomography and Recruitment-to-Inflation Ratio in Mechanically Ventilated Adults with Acute Respiratory Failure

What this Trial Is About

Researchers are evaluating lung recruitment potential in patients with acute respiratory failure who are mechanically ventilated. The study aims to compare and assess the consistency between three methods recruitment-to-inflation ratio RI ratio, two-dimensional electrical impedance tomography 2D-EIT, and three-dimensional electrical impedance tomography 3D-EIT. This observational study seeks to determine if these methods provide consistent predictions for lung recruitment potential during ventilator support. Participants will undergo a standardized positive end-expiratory pressure PEEP titration procedure while being monitored simultaneously by 2D- and 3D-EIT. The RI ratio will be measured at both high and low PEEP levels to evaluate lung recruitment. This process is done under sedation and analgesia, without spontaneous breathing, to optimize mechanical ventilation settings. During the study, patients will be closely monitored for lung recruitment using the mentioned diagnostic tests within 24 hours after enrollment. Data collected includes oxygenation levels and lung responses to PEEP adjustments. The study also includes safety monitoring for hemodynamic stability and contraindications to ensure patient well-being throughout the procedure.

Lung Recruitment Assessed by 2D/3D-EIT and R/I Ratio in Acute Respiratory Failure Patients With Mechanical Ventilation