Actively Recruiting
Magnetoencephalography by Optical Pumping Magnetometer for Brain Activity Assessment in Adults, Newborns, Premature Infants, and Pregnant Women
Led by Centre Hospitalier Universitaire, Amiens · Updated on 2025-05-28
70
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the use of Magnetoencephalography (MEG) with Optical Pumping Magnetometer (OPM) sensors to record brain activity in healthy adults, premature and full-term newborns, and pregnant women. This study aims to identify brain development biomarkers using MEG, which offers better time and spatial resolution than traditional EEG. The project focuses on comparing MEG with OPM sensors to high-resolution EEG, as OPM sensors do not require costly helium cooling like traditional SQUID sensors. Participants will undergo 40 minutes of MEG using the OPM technology. The study includes four groups: healthy adults aged 18 to 65, full-term newborns aged 38 to 42 weeks gestational age, premature newborns aged 28 to 36 weeks gestational age, and pregnant women between 28 and 40 weeks gestational age. This non-randomized study is single-masked and does not involve a placebo or comparison drug. During the study, researchers will measure the signal-to-noise ratio of MEG with OPM sensors and compare it to that of high-resolution EEG. Participants will be evaluated on a single day, with the primary outcomes focused on brain activity signal quality. Safety is monitored by excluding participants with devices that cause interference and those unable to remain still. The study will continue until April 2026, and participants will be involved in a short, focused session to assess brain activity.
CONDITIONS
Brief Title
Magnetoencephalography by Optical Pumping Magnetometer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 65 years
- No pathology or treatment for adult volunteers
- Term newborns between 38 and 42 weeks gestational age
- No pathology or treatment for term newborns
- Premature newborns between 28 and 36 weeks gestational age
- No pathology or treatment except routine care for prematurity in premature newborns
- Pregnant women between 28 and 40 weeks gestational age
- No pathology or treatment for pregnant women
You will not qualify if you...
- Presence of prosthesis or pacemaker that may interfere with MEG measurements
- Inability to remain still for a few minutes during the recording
- Newborns requiring ventilatory assistance or infusion
- Newborns not meeting the specified age criteria
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo 40 minutes of Magnetoencephalography with an Optical Pumping Magnetometer to assess brain activity.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
CHU Amiens
Amiens, France, 80054
Actively Recruiting
Research Team
F
Fabrice Wallois, Pr
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
4
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