Actively Recruiting
Investigation of the Effects of Mandibular Stretching Exercise and 4-4-8 Breathing Exercise on Autonomic Nervous System Activity, Muscle Tone, and Psychological State
Led by Mehin Mammadzada · Updated on 2026-03-16
52
Participants Needed
1
Research Sites
13 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying how mandibular stretching exercises and the 4-4-8 breathing technique affect the autonomic nervous system, muscle tone, and psychological well-being in healthy university students aged 18 to 30. This randomized controlled trial aims to better understand how these simple, non-invasive exercises might influence physiological and psychological responses through neuromuscular and respiratory mechanisms. Participants are randomly assigned to one of two groups: one group performs mandibular stretching exercises and the other performs the 4-4-8 breathing exercises. Both groups follow specific study protocols for their assigned interventions. Measurements are taken before and after the intervention to evaluate changes in autonomic nervous system activity, muscle tone, and psychological state. During the study, participants will undergo assessments of autonomic nervous system activity, muscle tone, and psychological status at baseline and at 20, 40, 80, and 120 minutes after performing the exercises. These repeated measurements help researchers monitor short-term effects of the interventions. The total duration involves initial baseline evaluation and follow-up measurements within a few hours after the exercises.
CONDITIONS
Brief Title
Mandibular Stretching and 4-4-8 Breathing Exercises on Autonomic Nervous System Activity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy university students
- Age between 18 and 30 years
- Voluntary participation in the study
- Ability to understand and perform mandibular stretching exercise and 4-4-8 breathing exercise
You will not qualify if you...
- History of neurological disorders
- Musculoskeletal disorders affecting the jaw, neck, or respiratory system
- Respiratory diseases
- Use of medications that may affect the autonomic nervous system
- Inability to perform the exercises required in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single session with follow-up assessments over 2 hours
Participants perform mandibular stretching exercises or 4-4-8 breathing exercises according to the study protocol.
1 baseline visit and 1 follow-up visit with assessments at 20, 40, 80, and 120 minutes after the intervention
Trial Site Locations
Total: 1 location
1
Necmettin Erbakan University
Konya, Konya, Turkey (Türkiye)
Actively Recruiting
Research Team
M
Mehin Mammadzada, MSc Student
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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