Actively Recruiting

Phase Not Applicable
Age: 18Years - 30Years
All Genders
Healthy Volunteers
ID07472010

Investigation of the Effects of Mandibular Stretching Exercise and 4-4-8 Breathing Exercise on Autonomic Nervous System Activity, Muscle Tone, and Psychological State

Led by Mehin Mammadzada · Updated on 2026-03-16

52

Participants Needed

1

Research Sites

13 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying how mandibular stretching exercises and the 4-4-8 breathing technique affect the autonomic nervous system, muscle tone, and psychological well-being in healthy university students aged 18 to 30. This randomized controlled trial aims to better understand how these simple, non-invasive exercises might influence physiological and psychological responses through neuromuscular and respiratory mechanisms. Participants are randomly assigned to one of two groups: one group performs mandibular stretching exercises and the other performs the 4-4-8 breathing exercises. Both groups follow specific study protocols for their assigned interventions. Measurements are taken before and after the intervention to evaluate changes in autonomic nervous system activity, muscle tone, and psychological state. During the study, participants will undergo assessments of autonomic nervous system activity, muscle tone, and psychological status at baseline and at 20, 40, 80, and 120 minutes after performing the exercises. These repeated measurements help researchers monitor short-term effects of the interventions. The total duration involves initial baseline evaluation and follow-up measurements within a few hours after the exercises.

CONDITIONS

Brief Title

Mandibular Stretching and 4-4-8 Breathing Exercises on Autonomic Nervous System Activity

Who Can Participate

Age: 18Years - 30Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy university students
  • Age between 18 and 30 years
  • Voluntary participation in the study
  • Ability to understand and perform mandibular stretching exercise and 4-4-8 breathing exercise
Not Eligible

You will not qualify if you...

  • History of neurological disorders
  • Musculoskeletal disorders affecting the jaw, neck, or respiratory system
  • Respiratory diseases
  • Use of medications that may affect the autonomic nervous system
  • Inability to perform the exercises required in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Single session with follow-up assessments over 2 hours

Participants perform mandibular stretching exercises or 4-4-8 breathing exercises according to the study protocol.

1 baseline visit and 1 follow-up visit with assessments at 20, 40, 80, and 120 minutes after the intervention

Trial Site Locations

Total: 1 location

1

Necmettin Erbakan University

Konya, Konya, Turkey (Türkiye)

Actively Recruiting

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Research Team

M

Mehin Mammadzada, MSc Student

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Frequently Asked Questions

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