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Study of How Maternal Expectations About Labor Pain Relief Affect Risk of Postpartum Depression

Led by University of Padova · Updated on 2026-04-29

3640

Participants Needed

1

Research Sites

21 weeks

Total Duration

AI-Summary

What this Trial Is About

Postpartum Depression PPD affects 15% to 20% of women within the first year after childbirth and can cause symptoms like low mood, anxiety, and insomnia, with potential long-term impacts on mother and child. This observational study evaluates whether meeting a mothers expectations about labor pain relief affects the risk of developing PPD. The research is sponsored by the University of Padova and focuses on understanding the relationship between labor analgesia expectations and postpartum mental health. Participants are grouped based on whether their prenatal expectations of labor analgesia matched the actual pain relief received. The interventions studied include epidural analgesia administered via catheter using local anesthetics with or without opioids upon request during labor, single-shot spinal analgesia, or no neuraxial analgesia at all. The study compares outcomes between those whose expectations were met and those whose were not. Women who plan a vaginal delivery will be followed to assess depressive symptoms shortly after birth and up to six months postpartum. Data collection includes measuring the incidence of postpartum depression six months after labor, early signs of depression within 24 to 48 hours after delivery, pain intensity at birth, and the effect of analgesia in those whose expectations were unmet. The study involves informed consent, monitoring, and questionnaires to evaluate psychological outcomes over time.

CONDITIONS

Brief Title

Maternal Expectations on Labor Analgesia and Risk of Postpartum Depression: An Observational Study

Research Team

F

Fabrizia Calabrese, MD

G

Giulia Faccioli, MD

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