Study Measuring Brain Electric Responses During Awake Neurosurgery for Low Grade Infiltrative Glioma OMS Type II

What this Trial Is About

Researchers are conducting an experimental study on patients with low-grade infiltrative glioma OMS Type II who will undergo awake brain surgery at the University Hospital of Montpellier. The study aims to understand how electrical impulses used by neurosurgeons to map brain function during surgery spread through the brain and to identify which nerve networks are inhibited by these impulses. This research involves detailed brain activity recordings before, during, and after tumor removal. During the awake neurosurgery, direct electrical stimulation will be applied to the brain while recording the brains electrical activity using electroencephalography EEG and electrocorticography ECoG. These recordings will capture the brains responses to stimulation, called evoked potentials, to analyze how the brain reacts to this mapping technique. Data collection and processing are overseen by specialized teams, ensuring quality and consent verification throughout the study. Participants will have their brains electrical activity recorded before surgery with EEG, and before and after tumor removal with ECoG. The collected data will be stored digitally and analyzed using specialized software to identify evoked potentials. The primary outcome measured is the evoked potential response within two months after surgery. The study involves close data monitoring, consent verification, and aims to provide detailed understanding of brain network responses during awake neurosurgery for low-grade glioma.

Measure of the Potential Evoked by Electric Stimulation