Actively Recruiting
Study of Lung Microbiome and Immune Response in Adults with Anti-MDA5 Antibody Positive Dermatomyositis and Interstitial Lung Disease
Led by Chinese PLA General Hospital · Updated on 2024-01-12
50
Participants Needed
1
Research Sites
47 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying the relationship between the microbial community, the immune system, and the presence or absence of rapidly progressive interstitial lung disease RPILD in patients with anti-MDA5 antibody positive dermatomyositis. This observational study aims to better understand how changes in microecology may affect disease development in this specific patient population. Bronchoalveolar lavage samples from patients diagnosed with anti-MDA5 antibody positive dermatomyositis and interstitial lung disease are collected and analyzed. The study focuses on examining the composition of the microbial community within these specimens to explore its connection to disease occurrence and progression. Participants will undergo bronchoalveolar lavage and provide samples for microbial analysis. Researchers will assess the relationship between the microbial community and interstitial lung disease presence over a 6-month period. The study includes clinical evaluations and monitoring of host immune responses to help understand disease mechanisms. The total participation duration corresponds to the 6-month outcome measurement timeframe.
CONDITIONS
Brief Title
Microecology and Immunity in Patients With Anti-MDA5 Antibody Positive Dermatomyositis and Interstitial Lung Disease
Research Team
Z
Zhimei Duan, doctor
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
