Mindfulness-based relapse prevention for substance use disorders: a pilot efficacy trial.
Sarah Bowen, Neharika Chawla, Susan E Collins...
https://pubmed.ncbi.nlm.nih.gov/19904665/Actively Recruiting
Led by University of Texas at Austin · Updated on 2026-08-07
80
Participants Needed
1
Research Sites
N/A
Total Duration
This research aims to evaluate Mindfulness-Based Relapse Prevention MBRP for substance use peer workers, comparing it to a standard referral to 12-step programs. The study focuses on reducing substance use, relapse risk, and burnout among peer workers. It also seeks to identify causes and risk factors for relapse, understand peer preferences for the intervention, adapt MBRP for this group, and assess its preliminary effectiveness and implementation. Participants will be randomly assigned to receive either the adapted MBRP intervention, which involves eight weekly 2-hour virtual sessions, or the standard care referral to 12-step programming. The trial is a pilot hybrid type 1 design and runs from August 2026 through July 2030. The goal is to compare these approaches in supporting peer workers at risk of substance use relapse. During the study, participants will complete four surveys assessing well-being outcomes and participate in one virtual interview about their experience. Researchers will measure changes in biologically verified and self-reported substance use, relapse warning signs, professional quality of life, and intervention feasibility and acceptability over six months. Secondary measures include coping, emotion regulation, perceived stress, mindfulness, and acceptance. The study tracks participants from enrollment through six months to understand the interventions impact and implementation.
CONDITIONS
Mindfulness-based Relapse Prevention for Peer Workers
K
Katie A McCormick, PhD, MSW
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University of Texas at Austin
Lead Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | Mindfulness-Based Relapse Prevention | 12-Step Referral (Standard of Care) |
|---|---|---|
| What it is | A structured group program, Mindfulness-Based Relapse Prevention (MBRP) provides eight weekly two-hour virtual sessions aiming to help peer workers develop mindfulness skills for managing substance use cravings and stress. | Standard of care involves referral to 12-step programming, a peer fellowship approach focusing on sobriety through group meetings and shared experiences among people with substance use history. |
| Role in trial | Investigational intervention being tested for reducing relapse risk and improving well-being in substance use peer workers. | Active comparator arm representing the usual peer support referral process. |
| Primary use | Group-based mindfulness training focused on preventing substance use relapse, managing cravings, and supporting long-term recovery. | Peer-driven group meetings based on the 12-step approach, aiming to maintain sobriety and prevent relapse. |
| How it is given or performed | Participants attend eight virtual group sessions, each lasting two hours, typically led by a trained facilitator. | Participants are referred to community-based, in-person or virtual 12-step meetings at regular frequency as chosen by the participant and available in their area. |
| Evidence status | Multiple randomized trials and meta-analyses in people with substance use disorders support MBRP's effectiveness in reducing relapse risk, especially following initial treatment. | 12-step programming is widely available and is associated with supporting recovery and sustained abstinence, but effectiveness compared to structured behavioral interventions may vary. |
| Important limitations | Access may be limited by availability of facilitators trained in mindfulness relapse prevention; effectiveness in peer worker populations is still being directly studied. | 12-step attendance and benefit rely on participant engagement, program fit, and local access. Outcomes can vary due to non-standardized delivery and voluntary participation. |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit (virtual)
Duration - 8 weeks
Participants will receive either the Mindfulness-Based Relapse Prevention intervention with eight weekly 2-hour virtual sessions or a referral to standard 12-step programming.
Weekly virtual sessions
Duration - 6 months
Participants complete surveys assessing substance use, relapse risk, burnout, and well-being at 1, 3, and 6 months after enrollment.
Four survey assessments and one virtual interview
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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Lead Sponsor