Actively Recruiting
Monitoring the Clinical and Immunological Effects of Microbiome Changes Following Severe Burn Injury
Led by Tamas Vegh, MD · Updated on 2026-01-09
30
Participants Needed
1
Research Sites
160 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this study is to longitudinally monitor dynamic changes in the gut microbiome following severe burn injury using fecal samples. Under standard nutritional protocols and intensive care management, serial fecal sampling is performed to assess alterations in microbiome diversity and composition, as well as the indirect effects of these changes on measurable inflammatory biomarkers, endocrine, hematological, immunological, and other organ-specific parameters, the clinical course, and patient outcomes.
CONDITIONS
Official Title
Monitoring the Clinical and Immunological Effects of Microbiome Changes Following Severe Burn Injury
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients between 18 and 65 years old with severe burn injury involving more than 20% of the total body surface area (TBSA) and/or inhalation injury
- Burn injury caused by scalding, flame, electrical, contact, or chemical exposure
- Hospital admission within 24 hours after the injury
You will not qualify if you...
- Patients with inflammatory bowel diseases or malignant tumors
- Patients with a history of major stomach or intestinal surgery
- Patients with a pre-injury ECOG performance status of 4
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Debrecen, Department of Anesthesiology and Intensive Care
Debrecen, Hajdú-Bihar, Hungary, 4032
Actively Recruiting
Research Team
L
Lenke Jenei Kluch, MD
CONTACT
E
Erzsebet Igbonu-Nagy, BSC
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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