Actively Recruiting
Analysis of the Relationship Between the Morphological Characteristics of the Maxillomandibular Region in a 3D Representation and the Refractive Status of the Eye After the Completion of Growth and Development
Led by University of Zagreb · Updated on 2026-03-10
120
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the relationship between the size and shape of the eye and the three-dimensional shape of the face in healthy young adults aged 21 to 25 years. The study aims to see if specific eye measurements relate to facial features after growth is complete and whether these relationships differ among people who are nearsighted, farsighted, or have normal vision. This observational study includes 120 participants divided into three refractive groups with balanced sex representation, all sharing the same ethnic background to reduce variability. Participants will undergo non-invasive eye examinations including measurements of visual acuity, refraction, and detailed eye biometry using the IOLMaster 700 device. Eye measurements include axial length, corneal curvature, anterior chamber depth, lens thickness, and corneal diameter. Additionally, three-dimensional facial imaging will be performed using a video-based photogrammetry system that creates detailed 3D facial models without radiation exposure. Facial landmarks and dimensions of various facial regions will be measured and analyzed. Participants' involvement includes ophthalmologic exams and 3D facial imaging conducted in a standardized manner by the same investigator to ensure consistency. Researchers will analyze correlations between eye measurements and facial features, comparing results across refractive groups. The primary outcome is axial length assessed once during the eye exam. Data will be securely stored and anonymized, with no additional risks beyond a routine eye exam expected. The study is approved by ethics committees and participation is voluntary with informed consent required.
CONDITIONS
Brief Title
Morphological Characteristics of the Maxillomandibular Region in a 3D Representation and the Refractive Status of the Eye
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy young adults aged 21 to 25 years
- Same ethnic background
- Best-corrected visual acuity of at least 1.0
- Normal findings of anterior and posterior ocular segments
- Refractive status confirmed by objective autorefractometry and subjective refraction
- Body mass index between 18.5 and 24.9 kg/m²
- Willingness to participate and provide written informed consent
You will not qualify if you...
- Previous ocular surgery
- Previous facial surgery
- Craniofacial anomalies
- Active or previous orthodontic therapy affecting maxillomandibular relationships
- Strabismus
- Amblyopia
- Ocular trauma
- Facial trauma
- Systemic diseases affecting facial morphology or ocular biometric parameters
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single day
Participants undergo non-invasive ophthalmologic examinations and three-dimensional facial imaging to collect biometric and morphometric data.
1 visit (in-person)
Duration - Up to study completion
Collected data including ophthalmologic and facial morphometric measurements are analyzed to evaluate the relationship between eye refractive status and maxillomandibular morphology.
No additional visits required
Trial Site Locations
Total: 1 location
1
University of Zagreb School of Dental Medicine
Zagreb, Croatia
Actively Recruiting
Research Team
M
Maja Malenica Ravlić, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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