Actively Recruiting
Mother Screening for Relapse Using Mid-upper Arm Circumference Among Children Recovered From Severe Acute Malnutrition
Led by University of California, San Francisco · Updated on 2025-11-20
2400
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of California, San Francisco
Lead Sponsor
C
Centre de Recherche en Sante de Nouna, Burkina Faso
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research investigates training caregivers to screen children who have recovered from severe acute malnutrition (SAM) using mid-upper arm circumference (MUAC) tapes. The study aims to find out if this training can reduce relapse risk to moderate or severe acute malnutrition and improve early detection times. It also evaluates how acceptable this screening method is to both caregivers and clinics. The trial involves children aged 6 to 54 months who recently recovered from uncomplicated SAM treated in outpatient programs. Participants are randomized into three groups: one receives usual care with no caregiver MUAC training and monthly clinic visits for 3 months plus a follow-up at 6 months; the second group receives caregiver MUAC screening training with weekly home screening plus the usual monthly clinic visits and a 6-month follow-up; the third group also receives caregiver MUAC screening training but with a reduced clinic visit schedule, attending only at 3 and 6 months post enrollment. Caregivers are counseled to bring their child to the clinic if their child's MUAC falls below 11.5 cm, indicating relapse. During the 6 months following enrollment, caregivers will screen their children weekly at home if trained, and all children will be assessed clinically at 3 and 6 months for outcomes. Researchers will measure relapse incidence, time to relapse detection, and anthropometric outcomes. Surveys will assess caregiver acceptance of MUAC training. The study plans to enroll 1200 caregiver-child pairs to better understand if caregiver screening improves relapse detection and child health after SAM recovery.
CONDITIONS
Brief Title
Mother Screening for Relapse Using Mid-upper Arm Circumference Among Children Recovered From Severe Acute Malnutrition (Full Scale Trial)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Caregivers aged 18 years or older or a legal guardian or relative aged 18 or older
- Child aged between 6 and 54 months
- Child has recovered from severe acute malnutrition according to national guidelines (weight-for-height ≥ -2 and/or mid-upper arm circumference ≥ 12.5 cm in the past month)
- Family plans to remain in the study area for 6 months
- Appropriate consent is provided by caregiver or guardian
You will not qualify if you...
- Caregiver or legal guardian or relative younger than 18 years old
- Child younger than 6 months or older than 54 months
- Twins or multiple births
- Children with feeding issues
- Child did not recover from severe acute malnutrition in the past month
- Family plans to move out of the study area within 6 months
- Caregiver or guardian refuses to provide consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 months
Caregivers are trained to screen their children for malnutrition relapse using mid-upper arm circumference tapes and asked to perform weekly screenings at home.
Weekly home screenings by caregivers
Duration - 6 months
Participants attend clinic visits to monitor child health with varying schedules depending on the assigned study arm.
Monthly clinic visits for 3 months and 1 visit at 6 months (standard schedule) or 1 visit at 3 months and 1 visit at 6 months (reduced schedule)
Trial Site Locations
Total: 1 location
1
Centre de recherche en sante de nouna
Nouna, Burkina Faso
Actively Recruiting
Research Team
C
Catherine Oldenburg, ScD
H
Hadley Burroughs
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
3
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