Actively Recruiting

Age: 40Years - 85Years
All Genders
Healthy Volunteers
ID06829433

Quantifying the Movement Dynamics of Adults Living With Total Knee Arthroplasty and Knee Osteoarthritis

Led by University of Portsmouth · Updated on 2025-02-21

36

Participants Needed

1

Research Sites

34 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research explores differences in walking and movement mechanics, exercise response, and physical activity among adults with knee osteoarthritis (OA), those who have had total knee replacement surgery, and healthy individuals. The study aims to better understand why people with OA or joint replacements tend to be less physically active despite pain relief from surgery. It focuses on identifying factors like unhealthy movement patterns and reduced fitness that may affect physical activity levels and quality of life. Participants include adults aged 40 to 85 with symptomatic knee OA, total knee replacement, or healthy controls. This is an observational cross-sectional study where participants undergo biomechanical movement testing without receiving any intervention. The study compares movement dynamics across groups to inform future treatments and rehabilitation strategies. During testing visits lasting about 2 hours, researchers assess peak knee adduction moments and other biomechanical measures. Participants also provide information on their physical activity and exercise responses. The study monitors walking ability and movement patterns to understand factors influencing physical function and activity. The overall goal is to improve clinical outcomes and quality of life for people with knee OA and those after joint replacement surgery.

CONDITIONS

Brief Title

Movement Dynamics of Knee Osteoarthritis and Total Knee Replacement

Who Can Participate

Age: 40Years - 85Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed symptomatic bilateral or unilateral knee osteoarthritis
  • Self-reported ability to walk without an aid for 10 minutes
  • Ability to ascend and descend stairs
  • No neurological conditions or other musculoskeletal pathology or injury impacting walking gait
Not Eligible

You will not qualify if you...

  • Unable to walk at 0.8 meters per second
  • Exclusion based on IMO screening
  • Non-English speaking
  • Lacking ability to consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 1 day

Participants undergo biomechanical movement testing to assess knee function and movement patterns.

1 visit (in-person, approximately 2 hours)

Long-term Monitoring

Duration - Up to study completion in September 2026

Participants are observed over time to understand movement dynamics without any intervention.

No scheduled visits; observational follow-up

Trial Site Locations

Total: 1 location

1

School of Psychology, Health and Sport Sciences, University of Portsmouth

Portsmouth, Hampshire, United Kingdom, PO1 2ER

Actively Recruiting

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Research Team

J

Josie Morris, BSc

J

Joseph Moore, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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