Actively Recruiting

Age: 18Years +
All Genders
NCT07359690

Multimodal Analysis of Endomyocardial Biopsies

Led by University Hospital, Essen · Updated on 2026-01-22

216

Participants Needed

1

Research Sites

152 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is to pursue a multimodal approach to identify the molecular signatures and immune signalling molecules of various myocardial diseases and thereby contribute to improving diagnosis and therapy. The main aim is: -Identification of molecular profiles (e.g., proteome, lipidome, metabolome) and immune signalling profiles that are specifically associated with different myocardial diseases and the post-heart transplantation course. Participants already receiving an endomyocardial biopsy as part of their regular medical care will be enrolled. An additional biopsy sample will be taken for the above mentioned research.

CONDITIONS

Official Title

Multimodal Analysis of Endomyocardial Biopsies

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged >18 years with a clinical indication for endomyocardial biopsy.
  • Patients capable of providing informed consent who have signed the consent form for participation in the study.
Not Eligible

You will not qualify if you...

  • Patients without a clinical indication for endomyocardial biopsy (EMB).
  • Pregnant individuals.
  • Patients incapable of providing informed consent.
  • Women of childbearing potential who are not using adequate contraception.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center Essen, University Hospital Essen, Germany

Essen, North Rhine-Westphalia, Germany, 45147

Actively Recruiting

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Research Team

L

Lars Michel, PD Dr. med.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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