Actively Recruiting
Natural History of Hypereosinophilia and Hypereosinophilic Syndromes
Led by University Hospital, Lille · Updated on 2026-02-20
600
Participants Needed
1
Research Sites
625 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Unexplained chronic hypereosinophilia (HE) and hypereosinophilic syndromes (HES) are heterogeneous regarding the organ involvements (heart, lungs, skin, .. or none), the evolutionary profiles, the response to treatments. Underlying mechanisms are largely unknown and may associate genetic predisposing factors (germinal ? somatic?), environmental factors (alimentation, tobacco use, hormones, infections, ..) The COHESion study aims to study all clinical and biological characteristics of HE/HES patients and their evolutionary profiles, with a focus on genetic factors and the mechanisms supporting transitory or persistant chronic HE/HES (in absence of any well identified extrinsic trigger like drugs, parasitosis, ..)
CONDITIONS
Official Title
Natural History of Hypereosinophilia and Hypereosinophilic Syndromes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men or women of any age
- Diagnosis of hypereosinophilia, hypereosinophilic syndrome, or specific organ eosinophilic disease according to ICOG-EO consensus criteria
- Absolute eosinophil count greater than 1500/mm3 or organ damage related to eosinophils regardless of cause
- Diagnosis of hypereosinophilic syndrome made since January 1, 2005
- Socially insured patients
- Patients who agree to participate and consent to the study procedures and duration
You will not qualify if you...
- Known HIV infection
- Not socially insured
- Unable to receive clear information about the study
- Refusal to sign informed consent
- Persons deprived of liberty
- Persons under legal protection such as guardianship or tutelage
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hôpital Roger Salengro, CHU
Lille, France
Actively Recruiting
Research Team
G
Guillaume Lefevre, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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