The effectiveness of rapid sequence intubation (RSI) versus non-RSI in emergency department: an analysis of multicenter prospective observational study.
Masashi Okubo, Koichiro Gibo, Yusuke Hagiwara...
https://pubmed.ncbi.nlm.nih.gov/28124199/Actively Recruiting
Led by King Abdulaziz University · Updated on 2022-08-16
1000
Participants Needed
1
Research Sites
8 weeks
Total Duration
Researchers are investigating the impact of oxygen desaturation during emergency intubation on brain function in critically ill, non-trauma adult patients. This observational study aims to understand whether low oxygen levels during intubation affect neurological outcomes, helping guide clinical practice to reduce these risks. The brains sensitivity to oxygen deprivation makes this an important focus, especially since emergency intubation can cause varying degrees of oxygen drop. Participants are grouped based on whether they experience hypoxia during intubation after induction but before the placement of the endotracheal tube. The study observes patients in emergency departments, critical care units, and inpatient floors undergoing emergent intubations as determined by their treating physicians. There are no investigational treatments given as this is an observational study. During the study, researchers assess neurological function using the Modified Rankin Scale up to 30 days post-intubation. They also monitor in-hospital mortality, ICU and hospital stay lengths, aspiration incidents within 14 days, and complications occurring within 24 hours of intubation. This comprehensive follow-up helps evaluate the consequences of hypoxia during emergency intubation in critically ill adults.
CONDITIONS
Neurologic Function Post Intubation
A
Abdullah Bakhsh
A
Asseil Bossei
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
King Abdulaziz University
Lead Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of intubation
Participants undergo emergent endotracheal intubation and are observed for oxygen desaturation during the procedure.
1 visit (in-person)
Duration - Up to 30 days
Participants are monitored for neurologic function and other outcomes following intubation.
Follow-up visits up to 30 days post-intubation
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Have more questions? Get in touch with our team for quick support
Masashi Okubo, Koichiro Gibo, Yusuke Hagiwara...
https://pubmed.ncbi.nlm.nih.gov/28124199/Endale Gebreegziabher Gebremedhn, Desta Mesele, Derso Aemero...
https://pubmed.ncbi.nlm.nih.gov/25548602/Ali Pourmand, Chelsea Robinson, Kelsey Dorwart...
https://pubmed.ncbi.nlm.nih.gov/28623005/R M Chesnut, L F Marshall, M R Klauber...
https://pubmed.ncbi.nlm.nih.gov/8459458/Jerry B Bodily, Heather R Webb, Steve J Weiss...
https://pubmed.ncbi.nlm.nih.gov/26164643/Edmund Tan, Osama Loubani, Nelofar Kureshi...
https://pubmed.ncbi.nlm.nih.gov/29687359/King Abdulaziz University
Lead Sponsor