Post Intubation Neurologic Outcomes in Critically Ill Adults

What this Trial Is About

Researchers are investigating the impact of oxygen desaturation during emergency intubation on brain function in critically ill, non-trauma adult patients. This observational study aims to understand whether low oxygen levels during intubation affect neurological outcomes, helping guide clinical practice to reduce these risks. The brain's sensitivity to oxygen deprivation makes this an important focus, especially since emergency intubation can cause varying degrees of oxygen drop. Participants are grouped based on whether they experience hypoxia during intubation after induction but before the placement of the endotracheal tube. The study observes patients in emergency departments, critical care units, and inpatient floors undergoing emergent intubations as determined by their treating physicians. There are no investigational treatments given as this is an observational study. During the study, researchers assess neurological function using the Modified Rankin Scale up to 30 days post-intubation. They also monitor in-hospital mortality, ICU and hospital stay lengths, aspiration incidents within 14 days, and complications occurring within 24 hours of intubation. This comprehensive follow-up helps evaluate the consequences of hypoxia during emergency intubation in critically ill adults.

Neurologic Function Post Intubation