Actively Recruiting
Neuromodulation With Spinal Stimulation Methods to Evaluate Motor Performance After Spinal Cord Injury
Led by University of Manitoba · Updated on 2025-02-10
24
Participants Needed
2
Research Sites
2 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating different methods of non-invasive spinal cord stimulation to improve motor function in people with spinal cord injuries (SCI) and those without injuries. This pilot study aims to compare voluntary and reflexive motor performance after applying two types of spinal stimulation and their respective sham (placebo) versions. The study focuses on assessing how these interventions affect motor pathways in paraplegic and non-injured individuals. Participants will receive spinal cord stimulation using either direct current stimulation or electrical pulsed stimulation for 15 minutes each, along with sham stimulations as controls. These procedures will occur in randomized sessions with double masking to compare effects fairly. The interventions are non-invasive and aim to modulate spinal cord activity using devices that deliver electrical stimulation transcutaneously. During the study, researchers will measure motor responses and motor evoked potentials immediately after stimulation within 1 to 15 minutes. They will also monitor blood pressure and any discomfort participants perceive during and shortly after stimulation. The study involves up to 24 participants and includes both people living with SCI and healthy volunteers. The total participation duration varies depending on the number of sessions and evaluations.
CONDITIONS
Brief Title
Neuromodulation With Spinal Stimulation Methods
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Spinal cord injury between vertebrae C4 and L4
- Ability to understand and follow directions
You will not qualify if you...
- History of seizures, head injury, concussion, or unexplained loss of consciousness
- Presence of implanted cochlear stimulator, brain/neurostimulator, cardiac pacemaker, or medication infusion device
- Presence of metal implants in the body
- Pregnancy
AI-Screening
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Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Single session of 15 minutes per stimulation type
Participants receive transcutaneous spinal stimulation or sham stimulation during experimental sessions to evaluate motor performance.
1 to multiple visits depending on crossover assignment
Trial Site Locations
Total: 2 locations
1
University of Manitoba
Winnipeg, Manitoba, Canada, R3E 0J9
Enrolling by Invitation
2
University of Manitoba
Winnipeg, Manitoba, Canada, R3E 0J9
Actively Recruiting
Research Team
K
Katinka Stecina, PhD
K
Kristine Cowley, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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