Study of Nociception Level NOL Index Use During Coronary Artery Bypass Surgery Under General Anesthesia

What this Trial Is About

Cardiac surgery often causes acute or chronic pain due to the bodys response to harmful stimuli during surgery under general anesthesia. This trial evaluates the use of a multiparametric device, the PMD200ae, which measures the Nociception Level Index NOL to monitor pain signals during cardiac surgery. The study aims to improve pain management by adjusting analgesic doses based on real-time nociception monitoring, particularly during coronary artery bypass grafting procedures. Participants will undergo on-pump cardiac surgery while the NOL monitor is used to assess nociception continuously. A finger probe connected to the PMD200ae device measures a single NOL index number ranging from 0 to 100 that reflects the level of nociception. This device integrates heart rate, pulse variability, skin conductance, and temperature to provide a comprehensive pain-related signal during surgery. Throughout the surgery, researchers will track the time the NOL monitor signal is lost in relation to the total surgery duration. This primary outcome assesses the feasibility of using the monitor during cardiac procedures. Participants will be evaluated at the time of surgery with no long-term follow-up detailed. The study focuses on monitoring effectiveness and device signal stability during the operative period.

Nociception Monitoring During Cardiac Surgery