Study Comparing Cooling Blanket and Non-cooling Blanket Effects on Body Temperature in Adults With Heat Stroke

What this Trial Is About

This clinical trial investigates the cooling effect of a cooling blanket in patients diagnosed with heat stroke. The study aims to determine the cooling rate of the cooling blanket and its relationship with patient outcomes, including prognosis improvement. Researchers want to see if using the cooling blanket can speed up body temperature reduction compared to standard cooling methods. Participants will be randomly assigned to one of two groups. One group receives standard cooling methods such as controlling emergency room temperature, fluid infusion at 46C, ice packs, evaporation, and convection without a cooling blanket. The other group receives the same standard cooling methods combined with a cooling blanket activated within 30 minutes of admission, set to 4-106C, targeting a body temperature of 386C. During the study, participants body temperatures will be measured at 0.5 hours and 2 hours after admission to the emergency department. Researchers will also monitor incidence of organ damage, length of ICU stay, and in-hospital mortality up to 90 days. The study evaluates the cooling speed and overall outcomes to compare the effectiveness of the cooling blanket versus non-cooling blanket methods.

Non-inferiority Study of the Effect of Non-cooling Blanket on Body Temperature in Patients With Heat Stroke